期刊： OPEN BIOLOGY, 2021; 11 (6)
A feature of metazoan reproduction is the elimination of maternal centrosomes from the oocyte. In animals that form syncytial cysts during oogenesis, ......
期刊： OPEN BIOLOGY, 2021; 11 (7)
Teleost fish are the most diverse group of vertebrates and provide opportunities to study the evolution of sex determination (SD) systems. Using genom......
期刊： OPEN BIOLOGY, 2021; 11 (4)
Identification of effective cardiac biomarkers and therapeutic targets for myocardial infarction (MI) will play an important role in early diagnosis a......
期刊： OPEN BIOLOGY, 2021; 11 (6)
Immune cell infiltration plays a key role in acute kidney injury (AKI) to chronic kidney disease (CKD) progression. T lymphocytes, neutrophils, monocy......
期刊： OPEN BIOLOGY, 2021; 11 (7)
Immunohistochemistry (IHC) using mouse retinal cryosections is widely used to study the expression and intracellular localization of proteins in mouse......
期刊： OPEN BIOLOGY, 2021; 11 (6)
Smoothened is a key receptor of the hedgehog pathway, but the roles of Smoothened in cardiac development remain incompletely understood. In this study......
期刊： OPEN BIOLOGY, 2021; 11 (6)
SIRT7 is a class III histone deacetylase that belongs to the sirtuin family. The past two decades have seen numerous breakthroughs in terms of underst......
期刊： OPEN BIOLOGY, 2021; 11 (7)
SUMOylation dynamically conjugates SUMO molecules to the lysine residue of a substrate protein, which depends on the physiological state of the cell a......
期刊： OPEN BIOLOGY, 2021; 11 (6)
Toxoplasma gondii is a ubiquitous pathogen infecting one-third of the global population. A significant fraction of toxoplasmosis cases is caused by re......
期刊： OPEN BIOLOGY, 2021; 11 (2)
In most bacteria, cell division begins with the polymerization of the GTPase FtsZ at mid-cell, which recruits the division machinery to initiate cell ......
期刊： OPEN BIOLOGY, 2021; 11 (2)
Non-ATPase regulatory subunits (Rpns) are components of the 26S proteasome involved in polyubiquitinated substrate recognition and deubiquitination in......
期刊： OPEN BIOLOGY, 2020; 10 (4)
Exosomes carrying microRNAs (miRNAs) have been demonstrated to play critical roles in the regulation of development, growth and metastasis of cancer. ......
期刊： OPEN BIOLOGY, 2020; 10 (5)
Cisplatin has been used as the first-line chemotherapy to treat advanced nasopharyngeal carcinoma (NPC), while acquired cisplatin resistance resulting......
期刊： OPEN BIOLOGY, 2020; 10 (7)
Anti-cancer peptides (ACPs) are a series of short peptides composed of 10-60 amino acids that can inhibit tumour cell proliferation or migration, or s......
期刊： OPEN BIOLOGY, 2020; 10 (8)
Diversity among highly specialized cells underlies the fundamental biology of complex multi-cellular organisms. One of the essential scientific questi......
