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Muscle multiorgan crosstalk with MG53 as a myokine for tissue repair and regeneration

期刊: CURRENT OPINION IN PHARMACOLOGY, 2021; 59 ()

Through stress and injury to tissues, the cell membrane is damaged and can lead to cell death and a cascade of inflammatory events. Soluble factors th......

Role of intestinal glucose absorption in glucose tolerance

期刊: CURRENT OPINION IN PHARMACOLOGY, 2020; 55 ()

Intestinal glucose absorption is integral to postprandial glucose homeostasis. Glucose absorption is dependent on a number of factors, including the e......

Modulation of gut microbiota to overcome resistance to immune checkpoint blockade in cancer immunotherapy

期刊: CURRENT OPINION IN PHARMACOLOGY, 2020; 54 ()

Immune checkpoint blockade therapies that target CTLA-4 and PD-1/PD-L1 have ushered in a new era of cancer treatment. Nevertheless, a significant prop......

Recent developments in unraveling signaling mechanisms underlying drug resistance due to cancer stem-like cells

期刊: CURRENT OPINION IN PHARMACOLOGY, 2020; 54 ()

Resistance in cancer cells to therapeutic measures is challenging and requires a rigorous delineation of the underlying mechanisms. Emerging findings ......

Evolution of fecal microbiota transplantation in methodology and ethical issues

期刊: CURRENT OPINION IN PHARMACOLOGY, 2019; 49 ()

Fecal microbiota transplantation (FMT), the core therapy for remodeling the gut microbiota with a long medical history, has gained great attention wor......

JIF:5.2

The regulatory roles of dietary fibers on host health via gut microbiota-derived short chain fatty acids

期刊: CURRENT OPINION IN PHARMACOLOGY, 2022; 62 ()

As a component of nutraceuticals, dietary fibers (DFs) are essential for maintain human growth and health via the regulation of gut microbiota in the ......

JIF:4.807

Antihypertensive effect of soybean bioactive peptides: A review

期刊: CURRENT OPINION IN PHARMACOLOGY, 2022; 62 ()

Hypertension is a global disease that is extremely harmful to humans. Timely lowering of blood pressure is necessary in order to avoid the occurrence ......

JIF:4.807

The potential pharmacological mechanisms of beta-hydroxybutyrate for improving cognitive functions

期刊: CURRENT OPINION IN PHARMACOLOGY, 2022; 62 ()

beta-Hydroxybutyl acid (DOHB), the most prevalent type of ketone in the human body, is involved in the pathogenesis of cognitive disorders, especially......

JIF:4.807

Paeoniflorin is a promising natural monomer for neurodegenerative diseases via modulation of Ca2+ and ROS homeostasis

期刊: CURRENT OPINION IN PHARMACOLOGY, 2022; 62 ()

Neurodegenerative diseases (NDDs) are a range of neurological disorders featured by neuronal degeneration and apoptosis. Cellular Calcium (Ca2+) and r......

JIF:4.807

Nutraceuticals use and type 2 diabetes mellitus

期刊: CURRENT OPINION IN PHARMACOLOGY, 2022; 62 ()

Type 2 diabetes mellitus (T2DM) is a complicated metabolic disease and has become one of the significant medical problems worldwide. Researchers aim t......

JIF:4.807

Novel strategies to promote resolution of inflammation to treat lower extremity artery disease

期刊: CURRENT OPINION IN PHARMACOLOGY, 2022; 65 ()

Lower extremity artery disease (LEAD) is a chronic inflammatory disease that occurs when atherosclerotic plaques form in the lower extremities, which ......

JIF:4.807

Potential mechanisms of macular degeneration protection by fatty fish consumption

期刊: CURRENT OPINION IN PHARMACOLOGY, 2022; 63 ()

Age-related macular degeneration (AMD) is a progressive retinal disease that is a leading cause of visual impairment and severe vision loss. The numbe......

JIF:4.807

Health benefits of spices in individuals with chemotherapeutic drug-induced cardiotoxicity

期刊: CURRENT OPINION IN PHARMACOLOGY, 2022; 63 ()

Cardio-oncology is an emerging field that mainly focuses on a series of cardiovascular diseases caused by chemotherapy and radiotherapy. In the histor......

JIF:4.807

Impaired metabolism of oligodendrocyte progenitor cells and axons in demyelinated lesion and in the aged CNS

期刊: CURRENT OPINION IN PHARMACOLOGY, 2022; 64 ()

The key pathology of multiple sclerosis (MS) comprises demyelination, axonal damage, and neuronal loss, and when MS develops into the progressive phas......

JIF:4.807

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