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Modulation of gut microbiota to overcome resistance to immune checkpoint blockade in cancer immunotherapy

Huang, JM; Jiang, ZB; Wang, YW; Fan, XQ; Cai, J; Yao, XJ; Liu, L; Huang, J; He, JX; Xie, C; Wu, QB; Cao, YB; Leung, ELH

Leung, ELH (corresponding author), Macau Univ Sci & Technol, Macau Inst Appl Res Med & Hlth, State Key Lab Qual Res Chinese Med, Macau, Peoples R China.; Leung, ELH (corresponding author), Guangzhou Med Univ, Affiliated Hosp 1, Guangzhou Inst Resp Hlth, Dept Thorac Surg, Guangzhou 510000, Guangdong, Peoples R China.; Leung, ELH (corresponding author), Guangzhou Med Univ, Affiliated Hosp 1, State Key Lab Resp Dis, Guangzhou 510000, Guangdong, Peoples R China.

CURRENT OPINION IN PHARMACOLOGY, 2020; 54 (): 1

Abstract

Immune checkpoint blockade therapies that target CTLA-4 and PD-1/PD-L1 have ushered in a new era of cancer treatment. Nevertheless, a significant prop......

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