期刊: TUMOR IMMUNOLOGY AND IMMUNOTHERAPY - CELLULAR METHODS, PT A, 2020; 631 ()
The formation of memory CD8(+) T cells is crucial for host protection upon reencounter of the same pathogen. Moreover, long-lasting anti-tumoral effec......
期刊: TUMOR IMMUNOLOGY AND IMMUNOTHERAPY - CELLULAR METHODS, PT B, 2020; 632 ()
Immunogenic cell death (ICD), induced by certain anticancer chemotherapeutics, leads to the emission of danger associated molecular patterns (DAMP) by......
期刊: TUMOR IMMUNOLOGY AND IMMUNOTHERAPY - CELLULAR METHODS, PT B, 2020; 632 ()
Immunogenic cell death (ICD), a functionally peculiar type of apoptosis, represents a unique way to deliver danger-associated molecular patterns (DAMP......
期刊: TUMOR IMMUNOLOGY AND IMMUNOTHERAPY - CELLULAR METHODS, PT B, 2020; 632 ()
Tumor cells treated by immunogenic cell death (ICD) inducers emit danger associated molecular patterns (DAMP), including but not limited to calreticul......
期刊: CHEMICAL AND SYNTHETIC BIOLOGY APPROACHES TO UNDERSTAND CELLULAR FUNCTIONS - PT C, 2020; 633 ()
Enzymes are pliable systems and core cellular components allowing the performance of several processes. They can also be utilized as "green" synthetic......
期刊: ENZYME ENGINEERING AND EVOLUTION: SPECIFIC ENZYME APPLICATIONS, 2020; 644 ()
Directed evolution is a well-established and powerful tool for enzyme engineering, which consists of iterative rounds of creating and screening a libr......
期刊: ENZYME ENGINEERING AND EVOLUTION: GENERAL METHODS, 2020; 643 ()
Directed evolution has emerged as the most productive enzyme engineering method, with stereoselectivity playing a crucial role when evolving mutants f......
期刊: ENZYME ENGINEERING AND EVOLUTION: GENERAL METHODS, 2020; 643 ()
The remolding active site loops via residue insertion/deletion as well as substitution is thought to play a key role in enzyme divergent evolution. Ho......
期刊: NEUTRON CRYSTALLOGRAPHY IN STRUCTURAL BIOLOGY, 2020; 634 ()
Dynamic nuclear polarization (DNP) can provide a powerful means to amplify neutron diffraction from biological crystals by 10-100-fold, while simultan......
期刊: CHEMICAL AND SYNTHETIC BIOLOGY APPROACHES TO UNDERSTAND CELLULAR FUNCTIONS - PT C, 2020; 633 ()
Phenotypic screening is a powerful approach to discover small molecules targeting pathways or disease biology with complex genetic causes. Following t......
期刊: CHEMICAL AND SYNTHETIC BIOLOGY APPROACHES TO UNDERSTAND CELLULAR FUNCTIONS - PT C, 2020; 633 ()
The cyclic-AMP response element binding protein (CREB) is an important nuclear transcription factor and has been shown to be overexpressed and/or over......
Histone ubiquitination plays critical roles in almost all the DNA-related processes, such as DNA replication, transcription and repair. The various ou......
Ortho-Phthalaldehyde (OPA)-amine reaction and OPA-amine-thiol reaction have been developed to effectively modify native peptides and proteins under th......
Near-infrared (NIR) fluorescent dyes with optimum photophysical properties are highly useful for bioimaging in living systems, but such dyes are still......
期刊: EXTRACELLULAR VESICLES, 2020; 645 ()
Extracellular vesicles (EVs) play a pivotal role in cancer progression. However, the majority of functional studies performed so far relies on data ac......