期刊: DRUG DEVELOPMENT RESEARCH, 2021; 82 (3)
Faced with the current large-scale public health emergency, collecting, sorting, and analyzing biomedical information related to the "SARS-CoV-2" shou......
期刊: DRUG DEVELOPMENT RESEARCH, ; ()
Parkinson's disease (PD) is a disabling neurodegenerative disease mainly caused by degeneration of mesencephalic dopaminergic neurons in the substanti......
期刊: DRUG DEVELOPMENT RESEARCH, ; ()
Glucocorticoids (GCs) can effectively control airway inflammation, but can also cause airway epithelial injury. Tectorigenin, a type of isoflavone iso......
期刊: DRUG DEVELOPMENT RESEARCH, ; ()
A series of compounds bearing 3 ',4 ',5 '-trimethoxy module into the core structure of evodiamine were designed and synthesized. The synthesized compo......
期刊: DRUG DEVELOPMENT RESEARCH, ; ()
Endothelial dysfunction is closely related to various cardiovascular diseases. Oxidative stress and apoptosis are involved in the progress of endothel......
期刊: DRUG DEVELOPMENT RESEARCH, ; ()
Azithromycin (AZM) has a therapeutic effect on diabetes, but there is no report on whether AZM has a therapeutic effect on diabetic nephropathy (DN) a......
期刊: DRUG DEVELOPMENT RESEARCH, ; ()
A series of novel indole-1,2,4-triazole derivatives have been designed, synthesized, and evaluated as potential tubulin polymerization inhibitors. The......
期刊: DRUG DEVELOPMENT RESEARCH, ; ()
Neobavaisoflavone (NBIF) is a flavonoid, which has a variety of pharmacological activities. However, the mechanism of NBIF in the treatment of osteopo......
期刊: DRUG DEVELOPMENT RESEARCH, ; ()
As an anti-tumor agent, histone deacetylases (HDACs) inhibitors have attracted wide attention. ACY1215 is a highly effective selective inhibitor of HD......
期刊: DRUG DEVELOPMENT RESEARCH, ; ()
The central nervous system (CNS) regulates and coordinates an extensive array of complex processes requiring harmonious regulation of specific genes. ......
期刊: DRUG DEVELOPMENT RESEARCH, ; ()
Oxidative stress plays a pivotal role in the pathogenesis of vitiligo. Paeonol, a phenolic compound found in the root bark of Cortex Moutan, has been ......
期刊: DRUG DEVELOPMENT RESEARCH, 2020; 81 (7)
Investigate the effect of flufenamic acid (FFA) on lung injury of sepsis rats. Rat sepsis model was established using cecal ligation and puncture (CLP......
期刊: DRUG DEVELOPMENT RESEARCH, 2020; 81 (7)
Ginsenoside Rg3, a ginsenoside isolated fromPanax ginseng, can regulate autophagy via AMP-activated protein kinase/mammalian target of rapamycin (AMPK......
期刊: DRUG DEVELOPMENT RESEARCH, 2020; 81 (8)
Background Curcumol was presented to unleash antitumor effects in a variety of cancers, including gastric cancer. However, the relevance between curcu......
期刊: DRUG DEVELOPMENT RESEARCH, 2020; 81 (5)
To improve water solubility, reduce phototoxicity and increase the tumor-targeting ability of hematoporphyrin (Hp) as a sonosensitizer for sonodynamic......