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Discovery of novel indole-1,2,4-triazole derivatives as tubulin polymerization inhibitors

Wu, MK; Man, RJ; Liao, YJ; Zhu, HL; Zhou, ZG

Man, RJ (corresponding author), Guangxi Univ Nationalities, Purificat & Modificat Res Platform, Guangxi Biol Polysaccharide Separat, Nanning 530006, Peoples R China.; Zhu, HL (corresponding author), Nanjing Univ, State Key Lab Pharmaceut Biotechnol, Nanjing 210023, Peoples R China.; Zhou, ZG (corresponding author), Guangxi Univ Nationalities, Guangxi Key Lab Polysaccharide Mat & Modificat, Coll Chem & Chem Engn, Nanning 530006, Peoples R China.

DRUG DEVELOPMENT RESEARCH, ; ():

Abstract

A series of novel indole-1,2,4-triazole derivatives have been designed, synthesized, and evaluated as potential tubulin polymerization inhibitors. The......

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