期刊： PHARMACEUTICAL CHEMISTRY JOURNAL, 2021; 55 (4)
Bacterial drug resistance has become a growing problem worldwide due to the excessive use of antibiotics in recent decades. Two small focused librarie......
期刊： PHARMACEUTICAL CHEMISTRY JOURNAL, 2021; 55 (1)
Cell-based screening of a privileged small molecule library led to the discovery of 9-sulfonyl-9(H)-purine as new scaffold for hepatitis C virus (HCV)......
期刊： PHARMACEUTICAL CHEMISTRY JOURNAL, 2021; 55 (1)
Ritter reactions of 3,4-(R-1)(2)-benzylcyanides with 1,1-(R-2)(2)-2-[3,4-(R-3)(2)-phenyl]ethanols synthesized 1-[3,4-(R-1)(2)-benzyl]-3,3-(R-2)(2)-6,7......
期刊： PHARMACEUTICAL CHEMISTRY JOURNAL, 2021; 54 (11)
Individual fractions containing significant quantities of lithium were obtained from an aqueous extract of Agrimonia pilosa; tannin fractions showed m......
期刊： PHARMACEUTICAL CHEMISTRY JOURNAL, 2021; 54 (10)
Two black rice pigment components, BR1 and BR2, were obtained by thin layer chromatography. From five experiments for in vitro testing of the scavengi......
期刊： PHARMACEUTICAL CHEMISTRY JOURNAL, 2021; 54 (10)
Solid dispersions (SDs) containing co-carrier were developed to improve in vitro dissolution and in vivo pharmacokinetics of celecoxib (CXB). Various ......
期刊： PHARMACEUTICAL CHEMISTRY JOURNAL, 2020; 54 (4)
Through a structure-based molecular hybridization strategy, a series of newN-acylhydrazone derivatives containing the benzothiazole and indole based m......
期刊： PHARMACEUTICAL CHEMISTRY JOURNAL, 2020; 54 (9)
Genistein is a phytoestrogen compound which possesses multiple biological activities such as anti-cancer, while its application is limited by poor pha......
期刊： PHARMACEUTICAL CHEMISTRY JOURNAL, 2020; 53 (11)
Ritter cyclocondensation of 2-(1-naphthyl)-1,1-(R-1)(2)-ethanols [R-1 = Me, 2R(1) = (CH2)(4)] with nitriles of general formula R2CN (acetonitrile, ben......
期刊： PHARMACEUTICAL CHEMISTRY JOURNAL, 2020; 53 (12)
A single-factor experiment for determining the extraction temperature, liquid-to-solid ratio, sonication time, and ethanol concentration was designed ......
期刊： PHARMACEUTICAL CHEMISTRY JOURNAL, 2020; 53 (12)
The current study was conducted to isolate and identify bioactive compounds from Sterculia diversifolia G. Don and to investigate their anti-glycation......
期刊： PHARMACEUTICAL CHEMISTRY JOURNAL, 0; ()
Six new glaucocalyxin A derivatives were synthesized by hydroxy substitution, their structures were elucidated on the basis of spectral analysis, and ......
期刊： PHARMACEUTICAL CHEMISTRY JOURNAL, 2019; 52 (10)
An effective and convenient process for the preparation of ticagrelor (1), an antiplatelet drug, has been developed. The synthesis of 1 is a four-step......
期刊： PHARMACEUTICAL CHEMISTRY JOURNAL, 0; ()
We have evaluated the antiproliferative activity of (E)-3-(3,5-difluorophenyl)-1-(2,4,6-trimethoxyphenyl)- prop-2-en-1-one (chalcone 5) against MGC-80......
期刊： PHARMACEUTICAL CHEMISTRY JOURNAL, 2019; 53 (7)
Medicines with the F3C-O group can increase the lipophilicity of an aromatic ring system and protect it from oxidative attacks. We have synthesized 3,......
