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Differentiation, functions, and roles of T follicular regulatory cells in autoimmune diseases

期刊: INFLAMMATION AND REGENERATION, 2021; 41 (1)

T follicular helper cells participate in stimulating germinal center (GC) formation and supporting B cell differentiation and autoantibody production.......

Prussian Blue@Polyacrylic Acid/Au Aggregate Janus Nanoparticles for CT Imaging-guided Chemotherapy and Enhanced Photothermal Therapy

期刊: ADVANCED THERAPEUTICS, 2020; 3 (10)

Janus nanoparticles (JNPs) have been widely researched for numerous biomedical applications. However, few studies have integrated enhanced phototherma......

Near-Infrared Fluorescence/Photoacoustic Agent with an Intensifying Optical Performance for Imaging-Guided Effective Photothermal Therapy

期刊: ADVANCED THERAPEUTICS, 2020; 3 (12)

Near-infrared fluorescent agents generally exhibit typical push-pull electron characteristics, and their optical behaviors are closely related to thei......

Soft and Condensed Nanoparticles and Nanoformulations for Cancer Drug Delivery and Repurpose

期刊: ADVANCED THERAPEUTICS, 2020; 3 (1)

Drug repurpose or reposition has been recently recognized as a high-performance strategy for developing therapeutic agents for cancer treatment. This ......

Dissolving Microneedles Loading TPGS Biphasic Functionalized PLGA Nanoparticles for Efficient Chemo-Photothermal Combined Therapy of Melanoma

期刊: ADVANCED THERAPEUTICS, 2020; 3 (6)

The poly (lactic-co-glycolic acid) nanoparticle (PLGA NP) has been widely used in the biomedical field. However, it is insensitive to degradation upon......

Gram-Positive Bacteria Cell Wall Driven Self-Disassembled Nanovesicles against Methicillin-Resistant Staphylococcus Aureus

期刊: ADVANCED THERAPEUTICS, 2020; 3 (6)

In the delivery system, high-performance targeting and local burst-releasing of antibiotics enable the enhancement of antipathogen efficacy and reduct......

DNA Vaccine Mediated by Rambutan-Like Mesoporous Silica Nanoparticles

期刊: ADVANCED THERAPEUTICS, 2020; 3 (1)

The development of safe and effective DNA vaccines is of great significance for treating various diseases. Mesoporous silica nanoparticles (MSNs) have......

Modularly Engineered Solid-Phase Synthesis of Aptamer-Functionalized Small Molecule Drugs for Targeted Cancer Therapy

期刊: ADVANCED THERAPEUTICS, 2020; 3 (9)

Biomarker-guided anticancer strategy has evolved into one of the most reliable and efficient cancer treatment techniques. However, most targeted antic......

Therapeutic non-invasive brain treatments in Alzheimer's disease: recent advances and challenges

期刊: INFLAMMATION AND REGENERATION, 2022; 42 (1)

Alzheimer's disease (AD) is one of the major neurodegenerative diseases and the most common form of dementia. Characterized by the loss of learning, m......

Quercetin enhances survival and axonal regeneration of motoneurons after spinal root avulsion and reimplantation: experiments in a rat model of brachial plexus avulsion

期刊: INFLAMMATION AND REGENERATION, 2022; 42 (1)

Background: Brachial plexus avulsion (BPA) physically involves the detachment of spinal nerve roots themselves and the associated spinal cord segment,......

Identification of molecular subtypes based on inflammatory response in lower-grade glioma

期刊: INFLAMMATION AND REGENERATION, 2022; 42 (1)

Background Inflammatory response is an important characteristic affecting prognosis and therapeutic response in lower-grade glioma (LGG). However, the......

Targeting microglial autophagic degradation of the NLRP3 inflammasome for identification of thonningianin A in Alzheimer's disease

期刊: INFLAMMATION AND REGENERATION, 2022; 42 (1)

Background NLRP3 inflammasome-mediated neuroinflammation plays a critical role in the pathogenesis and development of Alzheimer's disease (AD). Microg......

Imatinib inhibits pericyte-fibroblast transition and inflammation and promotes axon regeneration by blocking the PDGF-BB/PDGFR beta pathway in spinal cord injury

期刊: INFLAMMATION AND REGENERATION, 2022; 42 (1)

Background Fibrotic scar formation and inflammation are characteristic pathologies of spinal cord injury (SCI) in the injured core, which has been wid......

Research hotspots and trends for axon regeneration (2000-2021): a bibliometric study and systematic review

期刊: INFLAMMATION AND REGENERATION, 2022; 42 (1)

BackgroundAxons play an essential role in the connection of the nervous system with the rest of the body. Axon lesions often lead to permanent impairm......

Diet-induced obesity impairs spermatogenesis: the critical role of NLRP3 in Sertoli cells

期刊: INFLAMMATION AND REGENERATION, 2022; 42 (1)

Background: Accumulating evidence indicates a key role of Sertoli cell (SC) malfunction in spermatogenesis impairment induced by obesity. Nucleotide-b......

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