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Modularly Engineered Solid-Phase Synthesis of Aptamer-Functionalized Small Molecule Drugs for Targeted Cancer Therapy

Wang, D; Peng, YB; Deng, ZY; Tan, Y; Su, YY; Kuai, HL; Ai, LL; Huang, ZY; Wang, XQ; Zhang, XB; Tan, WH

Wang, XQ; Zhang, XB; Tan, WH (corresponding author), Hunan Univ, State Key Lab Chemo Biosensing & Chemometr, Collaborat Innovat Ctr Chem & Mol Med,Coll Biol, Mol Sci & Biomed Lab,Coll Chem & Chem Engn, Changsha 410082, Peoples R China.; Tan, WH (corresponding author), Shanghai Jiao Tong Univ, Sch Med, Renji Hosp, Inst Mol Med, Shanghai 200240, Peoples R China.; Tan, WH (corresponding author), Shanghai Jiao Tong Univ, Coll Chem & Chem Engn, Shanghai 200240, Peoples R China.; Tan, WH (corresponding author), Chinese Acad Sci, Univ Chinese Acad Sci, Canc Hosp, Inst Canc & Basic Med IBMC, Hangzhou 310022, Zhejiang, Peoples R China.

ADVANCED THERAPEUTICS, 2020; 3 (9):

Abstract

Biomarker-guided anticancer strategy has evolved into one of the most reliable and efficient cancer treatment techniques. However, most targeted antic......

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