期刊： CHEMMEDCHEM, 2021; 16 (15)
Accurate diagnosis and treatment have been extensively developed in the field of biomedicine, which put forward higher requirements for the developmen......
期刊： CHEMMEDCHEM, 2021; 16 (15)
Therapeutic peptides have attracted significant attention in clinical applications due to their advantages in biological origination and good biocompa......
期刊： CHEMMEDCHEM, 2021; 16 (16)
Photoacoustic imaging (PAI) in the second near-infrared window (NIR-II) is conducive to deep-tissue imaging due to small scattering coefficients, but ......
期刊： CHEMMEDCHEM, 2021; 16 (12)
The overexpression of histone deacetylase 8 (HDAC8) causes several diseases, and the selective inhibition of HDAC8 has been touted as a promising ther......
期刊： CHEMMEDCHEM, 2021; 16 (16)
With the advantage of inherent responsiveness that can change the spectroscopic signals from "off" to "on" state in responding to targets (e. g. biolo......
期刊： CHEMMEDCHEM, 2021; 16 (14)
Chemodynamic therapy (CDT) is an effective tumor treatment strategy in which Fe-II reacts with hydrogen peroxide (H2O2) in tumor cells to produce high......
期刊： CHEMMEDCHEM, 2021; 16 (18)
In silico screening predicted 1 (N-(4-((4-(3-(4-(3-methoxyphenyl)-1H-1,2,3-triazol-1-yl)propyl)piperazin-1-yl) sulfonyl)-phenyl)acetamide) as an inhib......
期刊： CHEMMEDCHEM, 2021; 16 (16)
Considering the high increase in mortality caused by cancer in recent years, cancer drugs with novel mechanisms of anticancer action are urgently need......
期刊： CHEMMEDCHEM, 2021; 16 (15)
Three series of new imidazole-fused imidazo[2,1-b][1,3,4]thiadiazole analogues (compounds 20 a-g, 21 a-g, and 22 a-g) have been synthesized, and their......
期刊： CHEMMEDCHEM, 2021; 16 (11)
Structure-based prediction of a compound's potential sites of metabolism (SOMs) mediated by cytochromes P450 (CYPs) is highly advantageous in the earl......
期刊： CHEMMEDCHEM, 2021; 16 (16)
Self-assembly peptide materials have promoted the development of science research including life science, optics, medicine, and catalysis over the pas......
期刊： CHEMMEDCHEM, 2021; 16 (17)
Immunotherapy is an effective way to mobilize the body's own immune system to confront tumor cells. However, the efficacy of immunotherapy is affected......
期刊： CHEMMEDCHEM, 2021; 16 (13)
The androgen receptor (AR) plays a crucial role in the occurrence and development of prostate cancer (PCa), and its signaling pathway remains active i......
期刊： CHEMMEDCHEM, 2021; 16 (16)
Lung cancer causes many deaths globally. Mutations in regulatory genes, irregularities in specific signal transduction events, or alterations of signa......
期刊： CHEMMEDCHEM, 2021; 16 (13)
Novel chiral ionone alkaloid derivatives were synthesized and their antimetastatic effects were evaluated in human breast cancer cells using chemotaxi......
