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Mechanosensitive calcium flashes promote sustained RhoA activation during tight junction remodeling

Varadarajan, S; Chumki, SA; Stephenson, RE; Misterovich, ER; Wu, JL; Dudley, CE; Erofeev, IS; Goryachev, AB; Miller, AL

Miller, AL (通讯作者),Univ Michigan, Dept Mol Cellular & Dev Biol, Ann Arbor, MI 48109 USA.;Miller, AL (通讯作者),Univ Michigan, Cellular & Mol Biol Program, Ann Arbor, MI 48109 USA.

JOURNAL OF CELL BIOLOGY, 2022; 221 (4):

Abstract

Epithelial cell-cell junctions remodel in response to mechanical stimuli to maintain barrier function. Previously, we found that local leaks in tight ......

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