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Exercise enhances mitochondrial fission and mitophagy to improve myopathy following critical limb ischemia in elderly mice via the PGC1a/FNDC5/irisin pathway

He, WY; Wang, P; Chen, QW; Li, CQ

Chen, QW (corresponding author), Chongqing Med Univ, Affiliated Hosp 2, Dept Geriatr Cardiol, 76 Linjiang Rd, Chongqing 400010, Peoples R China.

SKELETAL MUSCLE, 2020; 10 (1):

Abstract

Background Elderly populations are susceptible to critical limb ischemia (CLI), but conventional treatments cannot significantly decrease amputation a......

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