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Novel HIF-1 alpha inhibitor CDMP-TQZ for cancer therapy

Chu, PC; Wu, YC; Chen, CY; Hung, YS; Chang, CS

Chang, CS (corresponding author), China Med Univ, Drug Dev Ctr, Taichung 40402, Taiwan.; Chang, CS (corresponding author), China Med Univ, Sch Pharm, Coll Pharm, Taichung 40402, Taiwan.

FUTURE MEDICINAL CHEMISTRY, 2021; 13 (12): 1057

Abstract

Aim: Tumor cells adapt to hypoxic microenvironments by releasing the key transcription factor HIF-1 alpha, which promotes angiogenesis, glycolytic phe......

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