期刊： FUTURE MEDICINAL CHEMISTRY, 2021; 13 (12)
Aim: With the increasing abuse of antibacterial drugs, multidrug-resistant bacteria have become a burden on human health and the healthcare system. To......
期刊： FUTURE MEDICINAL CHEMISTRY, 2021; 13 (17)
Studies have shown that the FTO gene is closely related to obesity and weight gain in humans. FTO is an N-6-methyladenosine demethylase and is linked ......
期刊： FUTURE MEDICINAL CHEMISTRY, 2021; 13 (9)
Microtubules have been a concerning target of cancer chemotherapeutics for decades, and several tubulin-targeted agents, such as paclitaxel, vincristi......
期刊： FUTURE MEDICINAL CHEMISTRY, 2021; 13 (17)
Aim: To investigate whether kaempferol exhibited protective effects on osteoarthritis chondrocytes by modulating the XIST/miR-130a/STAT3 axis. Methods......
期刊： FUTURE MEDICINAL CHEMISTRY, 2021; 13 (14)
The GLUT is a key regulator of glucose metabolism and is widely expressed on the surface of most cells of the body. GLUT provides a variety of nutrien......
期刊： FUTURE MEDICINAL CHEMISTRY, 2021; 13 (10)
Wnt/beta-catenin signaling is crucial both in normal embryonic development and throughout the life of an organism. Moreover, aberrant Wnt signaling ha......
期刊： FUTURE MEDICINAL CHEMISTRY, 2021; 13 (10)
Glycogen phosphorylase (GP) is a key enzyme of glycogen catabolism, so it is significant to discover a new GP inhibitor. A series of benzazepinone der......
期刊： FUTURE MEDICINAL CHEMISTRY, 2021; 13 (15)
Background: A comprehensive approach to drug repositioning will be required to overcome translational hurdles and identify more neuroprotective drugs.......
期刊： FUTURE MEDICINAL CHEMISTRY, 2021; 13 (9)
Nonapoptotic types of regulated cell death have attracted widespread interest since the discovery that certain forms of cell necrosis can be regulated......
期刊： FUTURE MEDICINAL CHEMISTRY, 2021; 13 (12)
Aim: Tumor cells adapt to hypoxic microenvironments by releasing the key transcription factor HIF-1 alpha, which promotes angiogenesis, glycolytic phe......
期刊： FUTURE MEDICINAL CHEMISTRY, 2021; 13 (16)
Aim: CDK4 is a promising target for breast cancer therapy. This study aimed to explore the structure-activity relationship of CDK4 inhibitor abemacicl......
期刊： FUTURE MEDICINAL CHEMISTRY, 2021; 13 (13)
Background: Alzheimer's disease is a multifactorial neurological disorder seen in elderly people. Loss of cholinergic transmission and unbalanced tryp......
期刊： FUTURE MEDICINAL CHEMISTRY, 2021; 13 (17)
Background: Overexpression of LSD1 is associated with the occurrence of many diseases, including cancers, which makes LSD1 a significant target for an......
