Paeoniflorin ameliorates neuropathic pain-induced depression-like behaviors in mice by inhibiting hippocampal neuroinflammation activated via TLR4/NF-kappa B pathway-MedSci.cn

Paeoniflorin ameliorates neuropathic pain-induced depression-like behaviors in mice by inhibiting hippocampal neuroinflammation activated via TLR4/NF-kappa B pathway

Bai, HL; Chen, SZ; Yuan, TZ; Xu, DY; Cui, SB; Li, XD

Li, XD (corresponding author), Yanbian Univ, Ctr Morphol Expt, Med Coll, Yanji 133000, Jilin, Peoples R China.; Cui, SB (corresponding author), Yanbian Univ, Dept Neurol, Affiliated Hosp, Yanji 133000, Jilin, Peoples R China.

Abstract

Neuropathic pain (NP) that contributes to the comorbidity between pain and depression is a clinical dilemma. Neuroinflammatory responses are known to ......

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Paeoniflorin ameliorates neuropathic pain-induced depression-like behaviors in mice by inhibiting hippocampal neuroinflammation activated via TLR4/NF-kappa B pathway

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