Preferential Oxycodone Loss of Physically Manipulated Abuse Deterrent Oxycodone HCl Extended Release Tablets Prepared for Nasal Insufflation Studies-MedSci.cn

Preferential Oxycodone Loss of Physically Manipulated Abuse Deterrent Oxycodone HCl Extended Release Tablets Prepared for Nasal Insufflation Studies

Meng, ZJ; Boyce, HJ; Sun, DJ; Kinjo, M; Raofi, S; Li, TL

Li, TL (corresponding author), Purdue Univ, Dept Ind & Phys Pharm, RHPH Bldg,RM 124,575 Stadium Mall Dr, W Lafayette, IN 47907 USA.; Boyce, HJ (corresponding author), US FDA, Off Res & Stand, Off Gener Drugs, Ctr Drug Evaluat & Res, Bldg 75,RM 4692,10903 New Hampshire Ave, Silver Spring, MD 21231 USA.

Abstract

A method to reproducibly mill abuse deterrent oxycodone hydrochloride (HCl) extended release (ER) tablets was developed for a nasal insufflation pharm......

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Preferential Oxycodone Loss of Physically Manipulated Abuse Deterrent Oxycodone HCl Extended Release Tablets Prepared for Nasal Insufflation Studies

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