期刊： PHARMACEUTICAL RESEARCH, 2021; 38 (7)
Purpose Cyclodextrin (CD) is commonly used to enhance the solubility of oral drugs. However, with the increase of CD concentrations, the fraction of f......
期刊： PHARMACEUTICAL RESEARCH, 2021; 38 (8)
Purpose Topical treatment of various skin disorders requires drug absorption and penetration through the stratum corneum (SC) into the epidermis and d......
期刊： PHARMACEUTICAL RESEARCH, 2021; 38 (4)
Purpose To address the issue of local drug delivery in tumor treatment, a novel nanoparticle-hydrogel superstructure, namely semi-interpenetrating pol......
期刊： PHARMACEUTICAL RESEARCH, 2021; 38 (5)
Purpose Proper taste-masking formulation design is a critical issue for instant-dissolving tablets (IDTs). The purpose of this study is to use the ele......
期刊： PHARMACEUTICAL RESEARCH, 2021; 38 (8)
Purposes Liquid protein-based biopharmaceutical formulations have been reported to form aggregation and protein sub-visible particles (SbVPs) during d......
期刊： PHARMACEUTICAL RESEARCH, 2021; 38 (8)
Y Obesity expands as a global climbing epidemic that is often correlated to cardiovascular diseases and endocrine disorders. Converting white adipocyt......
期刊： PHARMACEUTICAL RESEARCH, 2021; 38 (6)
Purpose Application of multi-scale modelling workflows to characterise polymorphism in ritonavir with regard to its stability, bioavailability and pro......
期刊： PHARMACEUTICAL RESEARCH, 2021; 38 (5)
Purpose The involvement of the intestinally expressed xenobiotic transporters P-glycoprotein (P-gp) and Breast Cancer Resistance Protein (BCRP) have b......
期刊： PHARMACEUTICAL RESEARCH, 2021; 38 (7)
A method to reproducibly mill abuse deterrent oxycodone hydrochloride (HCl) extended release (ER) tablets was developed for a nasal insufflation pharm......
期刊： PHARMACEUTICAL RESEARCH, ; ()
Purpose From traditional monoclonal antibodies to more and more complex mAb-based formulations, biopharmaceutical faces one challenge after another. T......
期刊： PHARMACEUTICAL RESEARCH, ; ()
Purpose This study aims to overcome the challenges of the current oral targeted drug delivery system, such as the complex preparation process, poor bi......
期刊： PHARMACEUTICAL RESEARCH, 2021; 38 (1)
Purpose This study aimed to identify parameters that influence micafungin pharmacokinetics in Chinese patients with sepsis in the intensive care unit ......
期刊： PHARMACEUTICAL RESEARCH, 2021; 38 (2)
Purpose To formulate a xanthan gum-containing linezolid ophthalmic solution (LZD-XG) as a new antibiotic treatment against ocular bacterial infection.......
期刊： PHARMACEUTICAL RESEARCH, 2021; 38 (1)
Purposes To evaluate the effects of component contents in different colistin methanesulfonate (CMS) formulas on their clinical pharmacokinetics of the......
期刊： PHARMACEUTICAL RESEARCH, 2021; 38 (1)
Purpose Azelaic acid (AzA) is a dicarboxylic acid naturally occurring in various grains having anti-inflammatory and anti-oxidation properties. Recent......
