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Molecular mechanism of olesoxime-mediated neuroprotection through targeting alpha-synuclein interaction with mitochondrial VDAC

Rovini, A; Gurnev, PA; Beilina, A; Queralt-Martin, M; Rosencrans, W; Cookson, MR; Bezrukov, SM; Rostovtseva, TK

Rostovtseva, TK (reprint author), NICHHD, Sect Mol Transport, Eunice Kennedy Shriver, NIH, 9000 Rockville Pike,Bldg 29B,Room 1G09, Bethesda, MD 20892 USA.

CELLULAR AND MOLECULAR LIFE SCIENCES, 0; ():

Abstract

An intrinsically disordered neuronal protein alpha-synuclein (alpha Syn) is known to cause mitochondrial dysfunction, contributing to loss of dopamine......

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