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Interpretable SMILES-based QSAR Model of Inhibitory Activity of Sirtuins 1 and 2

Worachartcheewan, A; Toropova, AP; Toropov, AA; Pratiwi, R; Prachayasittikul, V; Nantasenamat, C

Worachartcheewan, A (corresponding author), Mahidol Univ, Fac Med Technol, Dept Community Med Technol, Bangkok 10700, Thailand.

COMBINATORIAL CHEMISTRY & HIGH THROUGHPUT SCREENING, 2021; 24 (8): 1217

Abstract

Background: Sirtuin 1 (Sirt1) and sirtuin 2 (Sirt2) are NAD(+)-dependent histone deacetylases which play important functional roles in the removal of ......

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