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Effect of Chemical Penetration Enhancer-Adhesive Interaction on Drug Release from Transdermal Patch: Mechanism Study Based on FT-IR Spectroscopy, C-13 NMR Spectroscopy, and Molecular Simulation

Luo, Z; Liu, C; Quan, P; Zhang, YM; Fang, L

Fang, L (corresponding author), Shenyang Pharmaceut Univ, Dept Pharmaceut Sci, 103 Wenhua Rd, Shenyang 110016, Liaoning, Peoples R China.

AAPS PHARMSCITECH, 2021; 22 (5):

Abstract

Chemical penetration enhancers (CPEs) are commonly added into transdermal patches to impart improved skin permeation of drug. However, significant une......

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