A particularly aggressive subtype of lung cancer with mutations in KRAS and LKB1 is shown to depend on increased hexosamine biosynthesis mediated by t......
Kim, J; Lee, HM; Cai, F; Ko, B; Yang, CD; Lieu, EL; Muhammad, N; Rhyne, S; Li, KL; Haloul, M; Gu, W; Faubert, B; Kaushik, AK; Cai, L; Kasiri, S; Marriam, U; Nham, K; Girard, L; Wang, H; Sun, XK; Kim, J; Minna, JD; Unsal-Kacmaz, K; DeBerardinis, RJ
Kim, J (corresponding author), Univ Illinois, Dept Biochem & Mol Genet, Chicago, IL 60607 USA.; DeBerardinis, RJ (corresponding author), UT Southwestern Med Ctr, Childrens Med Ctr, Res Inst, Dallas, TX 75390 USA.; DeBerardinis, RJ (corresponding author), UT Southwestern Med Ctr, Dept Pediat, Dallas, TX 75390 USA.; DeBerardinis, RJ (corresponding author), UT Southwestern Med Ctr, McDermott Ctr Human Growth & Dev, Dallas, TX 75390 USA.; DeBerardinis, RJ (corresponding author), UT Southwestern Med Ctr, Howard Hughes Med Inst, Dallas, TX 75390 USA.
NATURE METABOLISM, 2020; 2 (12):