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SIRT3 Transfection of Aged Human Bone Marrow-Derived Mesenchymal Stem Cells Improves Cell Therapy-Mediated Myocardial Repair

Zhang, DY; Gao, T; Xu, RJ; Sun, L; Zhang, CF; Bai, L; Chen, W; Liu, KY; Zhou, Y; Jiao, X; Zhang, GH; Guo, RL; Li, JX; Gao, Y; Jiao, WJ; Tian, H

Jiao, WJ (corresponding author), Qingdao Univ, Affiliated Hosp, Dept Thorac Surg, Qingdao 266000, Peoples R China.; Tian, H (corresponding author), Harbin Med Univ, Affiliated Hosp 2, Dept Cardiovasc Surg, Harbin 150086, Peoples R China.

REJUVENATION RESEARCH, 2020; 23 (6): 453

Abstract

Sirtuin 3 (SIRT3) is a deacetylase important for antioxidant protection, cell longevity, and aging. We hypothesized that SIRT3 improve oxidative resis......

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