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Age progression from vicenarians (20-29 year) to nonagenarians (90-99 year) among a population pharmacokinetic/pharmacodynamic (PopPk-PD) covariate analysis of propofol-bispectral index (BIS) electroencephalography

Dahaba, AA; Xiao, ZY; Zhu, XL; Dong, HL; Xiong, LZ; Rehak, P; Zelzer, S; Wang, K; Reibnegger, G

Xiao, ZY (corresponding author), Fourth Mil Med Univ, Xijing Hosp, Dept Anesthesiol, Xian, Shaanxi, Peoples R China.; Xiao, ZY (corresponding author), Dalian Med Univ, Affiliated Hosp 2, Dept Anesthesiol, 467 Zhongshan Rd, Dalian 116023, Peoples R China.

JOURNAL OF PHARMACOKINETICS AND PHARMACODYNAMICS, 2020; 47 (2): 145

Abstract

Background Pharmacokinetic/pharmacodynamic (PK/PD) modeling has made an enormous contribution to intravenous anesthesia. Because of their altered phys......

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