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Synthesis, in vitro stability, and antiproliferative effect of d-cysteine modified GnRH-doxorubicin conjugates

Li, ST; Zhao, HL; Chang, XM; Wang, JP; Zhao, EH; Yin, ZF; Mao, XX; Deng, SH; Hao, T; Wang, HN; Yang, YQ

Li, ST (reprint author), Chengde Med Univ, Hebei Prov Key Lab Res & Dev Tradit Chinese Med, Chengde 067000, Hebei, Peoples R China.

JOURNAL OF PEPTIDE SCIENCE, 2019; 25 (1):

Abstract

Overexpression of gonadotropin-releasing hormone (GnRH) receptor in many tumors but not in normal tissues makes it possible to use GnRH analogs as tar......

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