期刊: JOURNAL OF PEPTIDE SCIENCE, 2021; 27 (10)
Camptothecin (CPT), a DNA-toxin drug, exerts anticancer activity by inhibiting topoisomerase I. Targeted delivery of CPT into the cancer cell nucleus ......
期刊: JOURNAL OF PEPTIDE SCIENCE, 2021; 27 (10)
Infections with multidrug-resistant (MDR) pathogens are increasingly concerning for public health. Synthesized antimicrobial peptide A4 (SAMP-A4), a p......
期刊: JOURNAL OF PEPTIDE SCIENCE, 2021; 27 (8)
The goji berry is widely used as tonics; however, the antihuman cervical carcinoma effect and underlying mechanism of goji berry peptide remain to be ......
期刊: JOURNAL OF PEPTIDE SCIENCE, 2021; 27 (8)
Sulfonopeptides as the sulfur analogues of natural peptides have been widely used as enzyme inhibitors due to their tetrahedral sulfonamide moiety, wh......
期刊: JOURNAL OF PEPTIDE SCIENCE, 2021; 27 (9)
Antimicrobial peptide L163 was computationally designed by our laboratory; L163 is active against multidrug-resistant (MDR) bacteria but is easily deg......
期刊: JOURNAL OF PEPTIDE SCIENCE, ; ()
The bone morphogenetic protein-2 (BMP2) plays a crucial role in bone formation, growth and regeneration, which adopts a conformational wrist epitope a......
期刊: JOURNAL OF PEPTIDE SCIENCE, ; ()
We have examined in this contribution the composition dependence of binding characteristics in peptide-peptide interactions between an oligopeptide oc......
期刊: JOURNAL OF PEPTIDE SCIENCE, 2021; 27 (5)
In this article, a series of modifications were made on an antimicrobial peptide F2,5,12W, including altering the amino acid sequence, introducing cys......
期刊: JOURNAL OF PEPTIDE SCIENCE, 2021; 27 (4)
The ginseng has been used for over hundred years, in the belief of promoting longevity. However, the anticancer activity of ginseng leaf peptide (GP) ......
期刊: JOURNAL OF PEPTIDE SCIENCE, 2020; 26 (1)
Nonviral vector-based gene therapy is a promising strategy for treating a myriad of diseases. Cell-penetrating peptides are gaining increasing attenti......
期刊: JOURNAL OF PEPTIDE SCIENCE, 2020; 26 (8)
The inflammatory response plays important roles in acne vulgaris and pain pathogenesis. In previous study, Esc-1GN with anti-inflammatory, antimicrobi......
期刊: JOURNAL OF PEPTIDE SCIENCE, 2020; 26 (7)
Proliferation ofPropionibacterium acnes(P.acnes) is one of the main pathogenetic mechanisms of acne. Antimicrobial peptides with low-drug resistance a......
期刊: JOURNAL OF PEPTIDE SCIENCE, 2020; 26 (9)
We demonstrate in this contribution the evidence that significant cooperative binding effect can be identified for the amino acid sites that are deter......
期刊: JOURNAL OF PEPTIDE SCIENCE, 2020; 26 (11)
Presently, echinocandins have been recommended as the first-line drugs for the treatment of invasive candidiasis. However, low oral bioavailability an......
期刊: JOURNAL OF PEPTIDE SCIENCE, 2019; 25 (1)
Overexpression of gonadotropin-releasing hormone (GnRH) receptor in many tumors but not in normal tissues makes it possible to use GnRH analogs as tar......