Pluripotency exit is guided by the Peln1-mediated disruption of intrachromosomal architecture-MedSci.cn

Pluripotency exit is guided by the Peln1-mediated disruption of intrachromosomal architecture

Wang, YC; Jia, L; Wang, C; Du, ZH; Zhang, SL; Zhou, L; Wen, X; Li, H; Chen, HL; Nie, YY; Li, D; Liu, SS; Figueroa, DS; Ay, F; Xu, W; Zhang, SL; Li, W; Cui, JW; Hoffman, AR; Guo, H; Hu, JF

Wang, YC; Jia, L; Cui, JW; Hu, JF (通讯作者)，First Hosp Jilin Univ, Canc Ctr, Key Lab Organ Regenerat & Transplantat, Minist Educ, Changchun, Jilin, Peoples R China.;Wang, YC; Hoffman, AR; Guo, H (通讯作者)，First Hosp Jilin Univ, Dept Endocrinol, Changchun, Jilin, Peoples R China.;Wang, YC; Jia, L; Hu, JF (通讯作者)，Stanford Univ, VA Palo Alto Hlth Care Syst, Med Sch, Palo Alto, CA 94304 USA.

Abstract

Wang et al. identify Peln1 as a key chromatin lncRNA that controls the pluripotency exit in stem cells by trans regulating the Oct4 promoter and intra......

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Pluripotency exit is guided by the Peln1-mediated disruption of intrachromosomal architecture

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