Concentration-response modeling of ECG data from early-phase clinical studies to assess QT prolongation risk of contezolid (MRX-I), an oxazolidinone antibacterial agent-MedSci.cn

Concentration-response modeling of ECG data from early-phase clinical studies to assess QT prolongation risk of contezolid (MRX-I), an oxazolidinone antibacterial agent

Wu, JZ; Wang, K; Chen, YC; Yuan, H; Li, L; Zhang, J

Zhang, J (reprint author), Fudan Univ, Inst Antibiot, Huashan Hosp, Shanghai, Peoples R China.; Zhang, J (reprint author), Natl Hlth & Family Planning Commiss, Key Lab Clin Pharmacol Antibiot, Shanghai, Peoples R China.; Zhang, J (reprint author), Fudan U

Abstract

The effects of contezolid (MRX-I, an oxazolidinone antibacterial agent) on cardiac repolarization were evaluated retrospectively using a population mo......

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Concentration-response modeling of ECG data from early-phase clinical studies to assess QT prolongation risk of contezolid (MRX-I), an oxazolidinone antibacterial agent

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