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Activation of autophagy reverses gemcitabine-induced immune inhibition of RAW264.7 macrophages by promoting TNF-alpha, IL-6 and MHC-II expression

Jiang, SS; Wang, R; Han, L; Kuerban, K; Ye, L; Pan, S; Li, SN; Yuan, YF

Yuan, YF (corresponding author), Shanghai Jiao Tong Univ, Shanghai Peoples Hosp 9, Dept Pharm, Sch Med, Shanghai 200011, Peoples R China.

IMMUNOLOGIC RESEARCH, 2021; 69 (4): 352

Abstract

This research aims to investigate the effect of gemcitabine (GEM) on various activities and functions of macrophages. Phagocytosis, cell autophagy and......

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