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Dose Correction for a Michaelis-Menten Approximation of a Target-Mediated Drug Disposition Model with a Multiple Intravenous Dosing Regimens

Yan, XY; Ruixo, JJP; Krzyzanski, W

Yan, XY (corresponding author), Chinese Univ Hong Kong, Fac Med, Sch Pharm, Shatin, Hong Kong, Peoples R China.

AAPS JOURNAL, 2020; 22 (2):

Abstract

This study aimed to develop a method for implementing dose correction in a Michaelis-Menten (M-M) approximation of a target-mediated drug disposition ......

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