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Pterostilbene and its nicotinate derivative ameliorated vascular endothelial senescence and elicited endothelium-dependent relaxations via activation of sirtuin 1

Zhang, LL; Zheng, JW; Tie, X; Lin, T; Yang, WQ; Li, ZQ; Zou, Y; Guan, GM; Liu, PQ; Luo, WW; Li, ZM

Luo, WW; Li, ZM (corresponding author), Sun Yat Sen Univ, Sch Pharmaceut Sci, Dept Pharmacol & Toxicol, Guangzhou, Peoples R China.; Luo, WW; Li, ZM (corresponding author), Sun Yat Sen Univ, Natl & Local United Engn Lab Druggabil & New Drug, Guangzhou, Peoples R China.; Luo, WW; Li, ZM (corresponding author), Sun Yat Sen Univ, Guangdong Engn Lab Druggabil & New Drug Evaluat, Guangzhou, Peoples R China.

CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY, 2021; 99 (9): 900

Abstract

Vascular endothelial cell senescence is a leading cause of age-associated diseases and cardiovascular diseases. Interventions and therapies targeting ......

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