期刊: CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY, 2021; 99 (8)
Inflammation-induced activation and dysfunction of endothelial cells play an important role in the pathology of multiple vascular diseases. Nicaraven,......
期刊: CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY, 2021; 99 (9)
This study explored the potential effects of mild hyperhomocysteinemia (HHcy) on the blood-brain barrier (BBB) and neuroinflammation. Seven-week-old m......
期刊: CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY, 2021; 99 (6)
Excessively activated microglia exhibit increased migration, resulting in tissue damage and chronic inflammation. Src was confirmed to play an importa......
期刊: CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY, 2021; 99 (9)
Alamandine (ALA) and its receptor MrgD were recently identified as components of the renin-angiotensin system, which confer protection against cardio-......
期刊: CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY, 2021; 99 (5)
Various liver diseases caused by liver damage seriously affect people's health. The purpose of this study was to clarify the effects and the mechanism......
期刊: CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY, 2021; 99 (9)
Rosuvastatin has been found to possess antioxidant and anti-inflammatory properties. The aim of the current study was to evaluate whether rosuvastatin......
期刊: CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY, 2021; 99 (6)
Diabetic nephropathy (DN) is a common and complicated chronic kidney disease around the world. To elucidate and find effective therapies of DN is of v......
期刊: CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY, 2021; 99 (9)
Vascular endothelial cell senescence is a leading cause of age-associated diseases and cardiovascular diseases. Interventions and therapies targeting ......
期刊: CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY, 2021; 99 (9)
Metformin has been demonstrated to be beneficial for the treatment of an impaired myocardium as a result of ischemia/reperfusion (I/R) injury, and miR......
期刊: CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY, 2021; 99 (4)
Tetrahydroxystilbene glucoside (TSG), an active ingredient of Polygonum multiflorum, has been known for certain anti-aging effects. In this study, the......
期刊: CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY, 2021; 99 (8)
Metformin, the first medication that is often prescribed for the treatment of type 2 diabetes mellitus, was recently found to be neuroprotective. To s......
期刊: CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY, 2021; 99 (4)
The purpose of this study was to explore the differences between exhausted CD8(+) T cells in hepatocellular carcinoma (HCC) patients with and without ......
期刊: CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY, 2021; 99 (7)
Most sudden cardiac death in chronic heart failure (CHF) is caused by malignant ventricular arrhythmia (VA); however, the molecular mechanism remains ......
期刊: CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY, 2021; 99 (4)
Neutrophil extracellular traps (NETs) are extracellular DNA webs released from neutrophils to mediate the host antimicrobial defense. As NETs could al......
期刊: CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY, 2021; 99 (4)
Hypertrophic scar (HS) results from abnormal wound healing, accompanied by excessive hypercellularity, migration, and extracellular matrix (ECM) depos......