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Metformin attenuates ischemia/reperfusion-induced apoptosis of cardiac cells by downregulation of p53/microRNA-34a via activation of SIRT1

Li, WW; Jin, S; Hao, J; Shi, Y; Li, WJ; Jiang, LL

Jiang, LL (corresponding author), Hebei Med Univ, Dept Biochem & Mol Biol, 361 East Zhongshan Rd, Shijiazhuang 050011, Hebei, Peoples R China.

CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY, 2021; 99 (9): 875

Abstract

Metformin has been demonstrated to be beneficial for the treatment of an impaired myocardium as a result of ischemia/reperfusion (I/R) injury, and miR......

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