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Akkermansia muciniphila promotes type H vessel formation and bone fracture healing by reducing gut permeability and inflammation

Liu, JH; Yue, T; Luo, ZW; Cao, J; Yan, ZQ; Jin, L; Wan, TF; Shuai, CJ; Wang, ZG; Zhou, Y; Xu, R; Xie, H

Xie, H (corresponding author), Cent South Univ, Xiangya Hosp, Dept Orthoped, Changsha 410008, Hunan, Peoples R China.; Xie, H (corresponding author), Cent South Univ, Xiangya Hosp, Movement Syst Injury & Repair Res Ctr, Changsha 410008, Hunan, Peoples R China.; Zhou, Y (corresponding author), Cent South Univ, Xiangya Hosp 3, Dept Orthoped, Changsha 410013, Hunan, Peoples R China.; Xu, R (corresponding author), Cent South Univ, Xiangya Hosp 2, Dept Urol, Changsha 410008, Hunan, Peoples R China.; Xie, H (corresponding author), Cent South Univ, Xiangya Hosp, Dept Sports Med, Changsha 410008, Hunan, Peoples R China.; Xie, H (corresponding author), Hunan Key Lab Organ Injury Aging & Regenerat Med, Changsha 410008, Hunan, Peoples R China.; Xie, H (corresponding author), Hunan Key Lab Bone Joint Degenerat & Injury, Changsha 410008, Hunan, Peoples R China.; Xie, H (corresponding author), Cent South Univ, Xiangya Hosp, Natl Clin Res Ctr Geriatr Disorders, Changsha 410008, Hunan, Peoples R China.

DISEASE MODELS & MECHANISMS, 2020; 13 (11):

Abstract

Improving revascularization is one of the major measures in fracture treatment. Moderate local inflammation triggers angiogenesis, whereas systemic in......

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