期刊： DISEASE MODELS & MECHANISMS, 2022; 15 (6)
Chronic stress is one of the main risk factors for the onset of major depressive disorder. Chronic unpredictable mild stress results in reduced expres......
期刊： DISEASE MODELS & MECHANISMS, 2022; 15 (7)
Diagnostic tools for the early detection of renal injury caused by hyperuricemia are still lacking. Here, we investigated whether contrast-enhanced ul......
期刊： DISEASE MODELS & MECHANISMS, 2022; 15 (4)
An accurate prediction of the intracranial infiltration tendency and drug response of individual glioblastoma (GBM) cells is essential for personalize......
期刊： DISEASE MODELS & MECHANISMS, 2022; 15 (3)
Bietti crystalline dystrophy (BCD) is an autosomal recessive inherited retinal disease, resulting in blindness in most patients. The etiology and deve......
期刊： DISEASE MODELS & MECHANISMS, 2022; 15 (3)
Parkinson's disease (PD) is associated with alpha-synuclein-based Lewy body pathology, which has been difficult to observe in conventional two-dimensi......
期刊： DISEASE MODELS & MECHANISMS, 2022; 15 (1)
Development involves tightly paced, reproducible sequences of events, yet it must adjust to conditions external to it, such as resource availability a......
期刊： DISEASE MODELS & MECHANISMS, 2021; 14 (6)
The asymmetric distribution of phosphatidylserine (PS) in the cytoplasmic leaflet of eukaryotic cell plasma membranes is regulated by a group of P4-AT......
期刊： DISEASE MODELS & MECHANISMS, 2021; 14 (5)
Sporadic colorectal cancer (CRC) is a leading cause of worldwide cancer mortality. It arises from a complex milieu of host and environmental factors, ......
期刊： DISEASE MODELS & MECHANISMS, 2021; 14 (3)
Epidemiological research has shown that elevated serum urate concentration is a risk factor for the development of kidney disease; however, the mechan......
期刊： DISEASE MODELS & MECHANISMS, 2021; 14 (2)
Infantile myofibromatosis (IMF) is a benign tumor form characterized by the development of nonmetastatic tumors in skin, bone, muscle and sometimes vi......
期刊： DISEASE MODELS & MECHANISMS, 2021; 14 (2)
Multi-kinase RET inhibitors, such as cabozantinib and RXDX-105, are active in lung cancer patients with RET fusions; however, the overall response rat......
期刊： DISEASE MODELS & MECHANISMS, 2021; 14 (1)
Copper is an essential transition metal for all eukaryotes. In mammals, intestinal copper absorption is mediated by the ATP7A copper transporter, wher......
期刊： DISEASE MODELS & MECHANISMS, 2020; 13 (11)
Improving revascularization is one of the major measures in fracture treatment. Moderate local inflammation triggers angiogenesis, whereas systemic in......
期刊： DISEASE MODELS & MECHANISMS, 2020; 13 (11)
First Person is a series of interviews with the first authors of a selection of papers published in Disease Models & Mechanisms, helping earlycare......
期刊： DISEASE MODELS & MECHANISMS, 2020; 13 (8)
Model animals are indispensable for the study of human diseases, and in general, of complex biological processes. The Syrian hamster is an important m......
