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iRhom2 and TNF: Partners or enemies?

Badenes, M; Adrain, C

Badenes, M; Adrain, C (reprint author), IGC, Oeiras, Portugal.; Adrain, C (reprint author), Queens Univ, Ctr Canc Res & Cell Biol, Belfast, Antrim, North Ireland.

SCIENCE SIGNALING, 2019; 12 (605):

Abstract

iRhom2 is an essential cofactor for ADAM17, the metalloprotease that sheds both the proinflammatory cytokine tumor necrosis factor-alpha (TNF-alpha) a......

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