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BMX, a specific HDAC8 inhibitor, with TMZ for advanced CRC therapy: a novel synergic effect to elicit p53-, beta-catenin- and MGMT-dependent apoptotic cell death

Ko, HJ; Chiou, SJ; Tsai, CY; Loh, JK; Lin, XY; Tran, TH; Hou, CC; Cheng, TS; Lai, JM; Chang, PMH; Wang, FS; Su, CL; Huang, CYF; Hong, YR

Hong, YR (通讯作者),Kaohsiung Med Univ, Grad Inst Med, Coll Med, Kaohsiung 80708, Taiwan.;Huang, CYF; Hong, YR (通讯作者),Kaohsiung Med Univ, Coll Med, Dept Biochem, Kaohsiung 80708, Taiwan.

CELL COMMUNICATION AND SIGNALING, 2022; 20 (1):

Abstract

Background: Despite advances in treatment, patients with refractory colorectal cancer (CRC) still have poor long-term survival, so there is a need for......

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