SHMT2 promotes cell viability and inhibits ROS-dependent, mitochondrial-mediated apoptosis via the intrinsic signaling pathway in bladder cancer cells-MedSci.cn

SHMT2 promotes cell viability and inhibits ROS-dependent, mitochondrial-mediated apoptosis via the intrinsic signaling pathway in bladder cancer cells

Zhang, Y; Liu, Z; Wang, XL; Jian, H; Xiao, HH; Wen, TY

Wen, TY (通讯作者)，Chinese Acad Sci, Inst Microbiol, CAS Key Lab Pathogen Microbiol & Immunol, Beijing 100101, Peoples R China.;Wen, TY (通讯作者)，Chinese Acad Sci, Innovat Acad Green Manufacture, Beijing 100190, Peoples R China.;Wen, TY (通讯作者)，Univ Chinese Acad Sci, Savaid Med Sch, Beijing 100049, Peoples R China.

Abstract

Mitochondrial serine hydroxymethyltransferase (SHMT2) catalyzes the conversion of serine to glycine and concomitantly produces one-carbon units to sup......

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SHMT2 promotes cell viability and inhibits ROS-dependent, mitochondrial-mediated apoptosis via the intrinsic signaling pathway in bladder cancer cells

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