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A validated UHPLC-MS/MS method for simultaneous determination of lumiracoxib and its hydroxylation and acyl glucuronidation metabolites in rat plasma: Application to a pharmacokinetic study

Sun, J; Zhang, L; Zhang, LC; Liu, QW

Sun, J; Liu, QW (corresponding author), Zhengzhou Univ Peoples Hosp, Henan Prov Peoples Hosp, Dept Pharm, 7 Weiwu Rd, Zhengzhou 450003, Henan, Peoples R China.

JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2021; 201 ():

Abstract

Lumiracoxib is a selective cyclooxygenase-2 (COX-2) inhibitor. The aim of this study was to develop a simple and sensitive ultra-high performance liqu......

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