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Signaling by the integrated stress response kinase PKR is fine-tuned by dynamic clustering

Zappa, F; Muniozguren, NL; Wilson, MZ; Costello, MS; Ponce-Rojas, JC; Acosta-Alvear, D

Zappa, F; Acosta-Alvear, D (通讯作者),Univ Calif Santa Barbara, Dept Mol Cellular & Dev Biol, Santa Barbara, CA 93106 USA.;Zappa, F; Acosta-Alvear, D (通讯作者),Altos Labs Inc, Altos Labs Bay Area Inst Sci, Redwood City, CA 94065 USA.

JOURNAL OF CELL BIOLOGY, 2022; 221 (7):

Abstract

The double-stranded RNA sensor kinase PKR is one of four integrated stress response (ISR) sensor kinases that phosphorylate the a subunit of eukaryoti......

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