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Cyclooxygenase-2 Inhibitor Parecoxib Was Disclosed as a PPAR-gamma Agonist by In Silico and In Vitro Assay

Xiao, B; Li, DD; Wang, Y; Kim, EL; Zhao, N; Jin, SW; Bai, DH; Sun, LD; Jung, JH

Jung, JH (corresponding author), Pusan Natl Univ, Coll Pharm, Busan 46241, South Korea.; Sun, LD (corresponding author), Fourth Peoples Hosp Ordos, Ordos 017000, Peoples R China.

BIOMOLECULES & THERAPEUTICS, 2021; 29 (5): 519

Abstract

In a search for effective PPAR-gamma agonists, 110 clinical drugs were screened via molecular docking, and 9 drugs, including parecoxib, were selected......

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