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Dynamic Crowding Regulates Transcription

Shim, AR; Nap, RJ; Huang, K; Almassalha, LM; Matusda, H; Backman, V; Szleifer, I

Szleifer, I (corresponding author), Northwestern Univ, Dept Biomed Engn, Evanston, IL 60208 USA.; Szleifer, I (corresponding author), Northwestern Univ, Chem Life Proc Inst, Evanston, IL 60208 USA.; Szleifer, I (corresponding author), Northwestern Univ, Dept Chem, Evanston, IL 60208 USA.

BIOPHYSICAL JOURNAL, 2020; 118 (9): 2117

Abstract

The nuclear environment is highly crowded by biological macromolecules, including chromatin and mobile proteins, which alter the kinetics and efficien......

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