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Ebselen Reversibly Inhibits Human Glutamate Dehydrogenase at the Catalytic Site

Jin, YH; Li, D; Lu, SY; Zhao, H; Chen, Z; Hou, W; Ruan, BH

Ruan, BH (reprint author), Zhejiang Univ Technol, Coll Pharmaceut Sci, Collaborat Innovat Ctr Yangtze River Delta Reg Gr, Hangzhou 310014, Zhejiang, Peoples R China.

ASSAY AND DRUG DEVELOPMENT TECHNOLOGIES, 2018; 16 (2): 115

Abstract

Human glutamate dehydrogenase (GDH) plays an important role in neurological diseases, tumor metabolism, and hyperinsulinism-hyperammonemia syndrome (H......

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