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2020-05-29
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Nat Commun:EZH2介导的PP2A失活介导乳腺癌HER2靶向治疗的耐药性
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Cell Death & Disease:前列腺癌中靶向Wnt/EZH2/microRNA-708信号途径能够抑制神经纤维瘤分化
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Blood:MELK-EZH2泛素化或可成为NKTL的治疗新靶点
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Oncogene:在CRPC中,KDM8/JMJD5作为AR和PKM2的共激活子参与了AR/EZH2网络和肿瘤代谢
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Int J Cancer:多梳家族蛋白EZH2和EED在晚期前列腺癌中能够直接调控雄激素受体
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Lancet oncol:Tazemetostat,EZH2抑制剂,用于B细胞非霍奇金淋巴瘤和晚期固体肿瘤治疗效率良好,且安全性良好
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Blood:弥漫性大B细胞淋巴瘤通过激活存活信号通路或获得影响药物与靶点结合的EZH2突变,从而对EZH2抑制剂耐药
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CLIN CANCER RES:TOP2A和EZH2早期诊断侵袭性前列腺癌
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2018-06-04
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