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BMJ Open:创伤后应激障碍与心血管疾病事件相关

2016-01-11 phylis 译 MedSci原创

目的:创伤后应激障碍(PTSD)是心血管疾病(CVD)的危险因素。然而,另一种常见的应激障碍调节障碍与心血管疾病的风险增加是否相关,以及这种相关是否存在性别差异。本研究的目的是调查创伤后应激障碍和及调节障碍和4个心血管事件之间的整体和性别分层的相关性。设计:利用丹麦国家注册数据的一项前瞻性队列研究。设置:丹麦总人口。参与者:1995到2011年间,创伤后应激障碍(n = 4724)和调节障碍(N

目的:创伤后应激障碍(PTSD)是心血管疾病(CVD)的危险因素。然而,另一种常见的应激反应及适应障碍是否与心血管疾病的风险增加相关,以及这种相关是否存在性别差异尚不清楚。本研究的目的是调查创伤后应激障碍和适应障碍与4个心血管事件之间的整体和性别分层的相关性。

设计:利用丹麦国家注册数据的一项前瞻性队列研究。

设置:丹麦总人口。

参与者:1995到2011年间,创伤后应激障碍(n = 4724)和适应障碍(N = 64 855)与丹麦总人口相比。

主要预后:心血管事件包括心肌梗死(MI)、中风、缺血性中风和静脉血栓栓塞(VTE)。计算标准化发生率和95%CI。

结果:PTSD和4种CVD事件发生的相关性的范围,从MI 1.5(95% CI 1.1至1.9)到VTE的2.1(95% CI 1.7至2.7)。适应障碍和4种CVD事件相关性相似:从MI 的1.5(95% CI 1.4至1.6)到VTE的1.9(95% CI 1.8至2)。无性别差异。

结论:通过PTSD和应激反应及适应障碍的研究,表明应激相关的精神病理学与心血管时间相关。此外,应激障碍和心血管疾病的相关性的性别证据有限。

原文出处:

Gradus JL, Farkas DK, et al. Associations between stress disorders and cardiovascular disease events in the Danish population. BMJ Open. 2015 Dec 14

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    2016-10-02 feather89
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    2016-04-10 gaoxiaoe
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    2016-01-12 Lynee劲飞扬

    长见识了

    0

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    2016-01-12 huangshang9812

    0

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