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Hypertension:血压对绝经前后女性新发房颤的影响存在差异

2021-03-25 MedSci原创 MedSci原创

血压升高,尤其是收缩压升高是绝经前妇女新发房颤的重要危险因素。绝经后妇女血压和新发房颤风险之间的相关性明显减弱。收缩压升高对未服用降压药物的妇女新发房颤的影响更深远。

绝经前和绝经后妇女高血压的特点有所不同。高血压是新发心颤(AF)的已知危险因素,但其与绝经状态之间的相互作用尚未完全明确。

近日,血管权威杂志Hypertension上发表了一篇研究文章,研究人员利用以韩国全国人群为基础的队列调查了更年期是否会影响高血压对新发房颤的不良影响。

接受了国家健康检查和癌症筛查项目的个人都被纳入了这项研究。该研究共有3280834名女性接受评估,包含23781070人次每年随访数据。1439161名妇女经历了更年期。

绝经前女性新发房颤的风险与血压呈线性关系(收缩压和舒张压均P<0.001),与对照组(100 mmHg≤收缩压<110 mm Hg;风险比=1.588 [95%CI为1.383-1.823])相比,收缩压≥160 mmHg的绝经前女性新发房颤的风险增加58.8%。然而,在绝经后妇女中,血压和新发房颤的风险之间并没有观察到一致的相关性。在未服用降压药的患者中,血压升高会导致新发房颤的风险增加更为显著(交互作用P<0.001)。

综上所述,血压升高,尤其是收缩压升高是绝经前妇女新发房颤的重要危险因素。绝经后妇女血压和新发房颤风险之间的相关性明显减弱。收缩压升高对未服用降压药物的妇女新发房颤的影响更深远

原始出处:

Yun Gi Kim.et al.Different Influence of Blood Pressure on New-Onset Atrial Fibrillation in Pre- and Postmenopausal Women A Nationwide Population-Based Study.Hypertension.2021.https://www.ahajournals.org/doi/10.1161/HYPERTENSIONAHA.120.16513

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    2022-03-05 feather89
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  7. [GetPortalCommentsPageByObjectIdResponse(id=2039252, encodeId=ed86203925273, content=<a href='/topic/show?id=b45d1e274e8' target=_blank style='color:#2F92EE;'>#TENS#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=17274, encryptionId=b45d1e274e8, topicName=TENS)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3b172500206, createdName=12498ebem19暂无昵称, createdTime=Sat Dec 25 02:03:48 CST 2021, time=2021-12-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1728889, encodeId=1ac91e28889cc, content=<a href='/topic/show?id=986913980dd' target=_blank style='color:#2F92EE;'>#PE#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=69, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13980, encryptionId=986913980dd, topicName=PE)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f06c33759375, createdName=feather89, createdTime=Sat Mar 05 23:03:48 CST 2022, time=2022-03-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1636029, encodeId=985316360299f, content=<a href='/topic/show?id=b87ce888080' target=_blank style='color:#2F92EE;'>#绝经前#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=73, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=78880, encryptionId=b87ce888080, topicName=绝经前)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=7e8e22571454, createdName=ms5768352621950538, createdTime=Mon Nov 01 02:03:48 CST 2021, time=2021-11-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1257264, encodeId=2eb0125e26452, content=<a href='/topic/show?id=cdfce8879b1' target=_blank style='color:#2F92EE;'>#绝经#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=94, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=78879, encryptionId=cdfce8879b1, topicName=绝经)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a12645, createdName=yeye5224612, createdTime=Sat Mar 27 12:03:48 CST 2021, time=2021-03-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1481393, encodeId=b1e7148139322, content=<a href='/topic/show?id=ce0258131ff' target=_blank style='color:#2F92EE;'>#新发房颤#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=89, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=58131, encryptionId=ce0258131ff, topicName=新发房颤)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=788d7780866, createdName=若水125, createdTime=Sat Mar 27 12:03:48 CST 2021, time=2021-03-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1501529, encodeId=32b1150152976, content=<a href='/topic/show?id=f2db9238f9' target=_blank style='color:#2F92EE;'>#Hypertension#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=90, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=9238, encryptionId=f2db9238f9, topicName=Hypertension)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=11ff9497046, createdName=jambiya, createdTime=Sat Mar 27 12:03:48 CST 2021, time=2021-03-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1031365, encodeId=140a10313650c, content=房颤,临床上碰到很多哦, beContent=null, objectType=article, channel=null, level=null, likeNumber=124, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=心介, createdTime=Fri Mar 26 00:03:48 CST 2021, time=2021-03-26, status=1, ipAttribution=)]
    2021-03-26 心介

    房颤,临床上碰到很多哦

    0

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