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JAMA Netw Open:降低绝经后女性髋部骨折风险的日常生活小妙招——轻度活动与步行

2019-11-08 国际糖尿病编辑部 国际糖尿病

对于绝经后女性而言,预防骨折尤其是髋部骨折风险是非常重要的一件事情。那么,日常生活中,有哪些小举措有助于实现这一点?近期,一项最新研究发现,定期每周进行适度体育锻炼如户外劳动和步行有助于降低老年女性总体及髋部骨折风险。

对于绝经后女性而言,预防骨折尤其是髋部骨折风险是非常重要的一件事情。那么,日常生活中,有哪些小举措有助于实现这一点?近期,一项最新研究发现,定期每周进行适度体育锻炼如户外劳动和步行有助于降低老年女性总体及髋部骨折风险。

研究概要

美国布法罗大学的Michael J. LaMonte教授等人对妇女健康计划中1993~1998年间77206例50~79岁绝经后女性的数据进行了分析。受试者的平均年龄为63岁,白种人女性占85.6%,伴有骨质疏松者占8.4%,接受骨质疏松治疗者占3.9%。中位随访14年期间,共计25516例女性(33.1%)曾经发生了至少一次骨折。

主要结果

研究人员将以每项活动的代谢当量(MET)强度值乘以每周自我报告的体力活动时间作为衡量体力活动量的指标。分析显示,与不活动者(体力活动0 MET/周)相比,体力活动水平<7.5 MET/周、7.5~17.7 MET/周及>17.7 MET/周女性发生总体骨折的HR分别为0.94(95%CI:0.9~0.98)、0.95(95%CI:0.91~0.99)和0.94(95%CI:0.9~0.98);体力活动水平最高三分位距者发生髋部骨折的风险可降低18%(HR=0.82,95%CI:0.72~0.95)。此外,研究发现,与不活动者相比,快速步行的女性、轻度活动女性、中等~剧烈活动女性及从事庭院工作的女性发生髋部骨折的风险均更低;HR分别为0.88(95%CI:0.78~0.98)、0.82(95%CI:0.73~0.93)、0.88(95%CI:0.81~0.96)和0.9(95%CI:0.82~0.99)。

进一步分析发现,与不活动相比,总体力活动>17.7 MET/周可增加膝关节骨折风险(HR=1.26, 95%CI:1.05~1.5);而轻度活动则可降低临床椎体骨折(HR=0.87,95CI:0.78~0.96)及总体骨折(HR=0.91,95%CI:0.87~0.94)风险;中等至剧烈活动可增加腕部或前臂骨折风险(HR=1.09,95%CI:1.03~1.15)。

此外,研究发现,与不从事庭院工作相比,每周庭院工作超过6MET可降低总体骨折及髋部骨折风险[HR分别为0.95(95%CI:0.92~0.98)和0.9(95%CI:0.82~0.99)]。校正年龄后对久坐时间进行分析可见,每年坐立或躺着的时间达到9.5小时可增加髋部骨折、椎体骨折及总体骨折风险,HR分别为1.11(95%CI:1.01~1.21)、1.09(95%CI:1.01~1.17)和1.1(95%CI:1.07~1.13)。

研究提示

研究结果提示,轻度活动如步行及庭院工作可能有益于降低老年女性骨折风险,若未来能有更多研究证实这一点,则轻度活动将有望成为绝经后女性尤其是体弱且无法安全从事剧烈运动者预防骨折发生的重要措施。此外,未来有必要进一步研究确定久坐能否作为个体发生骨折的独立危险因素。

原始出处:
Michael J. LaMonte, et al. Association of Physical Activity and Fracture Risk Among Postmenopausal Women. JAMA Netw Open. October 25, 2019.


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    2022-07-23 小小医者

    #髋部骨折##骨质疏松#的重要并发症

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    2020-04-29 canlab
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    2020-03-26 yuanming15
  4. 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status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1390414, encodeId=959b139041435, content=<a href='/topic/show?id=22c6101695c9' target=_blank style='color:#2F92EE;'>#骨折风险#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=50, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=101695, encryptionId=22c6101695c9, topicName=骨折风险)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=21015, createdName=heli0118, createdTime=Sun Nov 10 13:01:00 CST 2019, time=2019-11-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1408500, encodeId=9d1c140850033, content=<a href='/topic/show?id=92021020e814' target=_blank style='color:#2F92EE;'>#髋部#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=61, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=102078, encryptionId=92021020e814, topicName=髋部)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=293f2750231, createdName=liuquan, createdTime=Sun Nov 10 13:01:00 CST 2019, time=2019-11-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1526651, encodeId=2649152665156, content=<a href='/topic/show?id=2fe6e88863a' target=_blank style='color:#2F92EE;'>#绝经后女性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=78886, encryptionId=2fe6e88863a, topicName=绝经后女性)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=b55511745984, createdName=chenhongpeng, createdTime=Sun Nov 10 13:01:00 CST 2019, time=2019-11-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1631622, encodeId=3425163162219, content=<a href='/topic/show?id=6395e888343' target=_blank style='color:#2F92EE;'>#绝经后#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=78883, encryptionId=6395e888343, topicName=绝经后)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=395f25, createdName=爆笑小医, createdTime=Sun Nov 10 13:01:00 CST 2019, time=2019-11-10, status=1, ipAttribution=)]
    2020-09-28 feather89
  5. [GetPortalCommentsPageByObjectIdResponse(id=1234134, encodeId=71c6123413411, content=<a href='/topic/show?id=baaa1020837e' target=_blank style='color:#2F92EE;'>#髋部骨折#</a>是<a href='/topic/show?id=fd3a1018623d' target=_blank style='color:#2F92EE;'>#骨质疏松#</a>的重要并发症, beContent=null, objectType=article, channel=null, level=null, likeNumber=164, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=102083, encryptionId=baaa1020837e, topicName=髋部骨折), TopicDto(id=101862, encryptionId=fd3a1018623d, topicName=骨质疏松)], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/Random/55971dc507c93968175ce7cc1e177b372a83869f.jpg, createdBy=f63e4754896, createdName=小小医者, createdTime=Sat Jul 23 03:20:00 CST 2022, time=2022-07-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1734184, encodeId=5c191e341848b, content=<a href='/topic/show?id=d4f412668a4' target=_blank style='color:#2F92EE;'>#NET#</a>, beContent=null, objectType=article, 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status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1390414, encodeId=959b139041435, content=<a href='/topic/show?id=22c6101695c9' target=_blank style='color:#2F92EE;'>#骨折风险#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=50, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=101695, encryptionId=22c6101695c9, topicName=骨折风险)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=21015, createdName=heli0118, createdTime=Sun Nov 10 13:01:00 CST 2019, time=2019-11-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1408500, encodeId=9d1c140850033, content=<a href='/topic/show?id=92021020e814' target=_blank style='color:#2F92EE;'>#髋部#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=61, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=102078, encryptionId=92021020e814, topicName=髋部)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=293f2750231, createdName=liuquan, createdTime=Sun Nov 10 13:01:00 CST 2019, time=2019-11-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1526651, encodeId=2649152665156, content=<a href='/topic/show?id=2fe6e88863a' target=_blank style='color:#2F92EE;'>#绝经后女性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=78886, encryptionId=2fe6e88863a, topicName=绝经后女性)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=b55511745984, createdName=chenhongpeng, createdTime=Sun Nov 10 13:01:00 CST 2019, time=2019-11-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1631622, encodeId=3425163162219, content=<a href='/topic/show?id=6395e888343' target=_blank style='color:#2F92EE;'>#绝经后#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=78883, encryptionId=6395e888343, topicName=绝经后)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=395f25, createdName=爆笑小医, createdTime=Sun Nov 10 13:01:00 CST 2019, time=2019-11-10, status=1, ipAttribution=)]
  6. [GetPortalCommentsPageByObjectIdResponse(id=1234134, encodeId=71c6123413411, content=<a href='/topic/show?id=baaa1020837e' target=_blank style='color:#2F92EE;'>#髋部骨折#</a>是<a href='/topic/show?id=fd3a1018623d' target=_blank style='color:#2F92EE;'>#骨质疏松#</a>的重要并发症, beContent=null, objectType=article, channel=null, level=null, likeNumber=164, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=102083, encryptionId=baaa1020837e, topicName=髋部骨折), TopicDto(id=101862, encryptionId=fd3a1018623d, topicName=骨质疏松)], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/Random/55971dc507c93968175ce7cc1e177b372a83869f.jpg, createdBy=f63e4754896, createdName=小小医者, createdTime=Sat Jul 23 03:20:00 CST 2022, time=2022-07-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1734184, encodeId=5c191e341848b, content=<a href='/topic/show?id=d4f412668a4' target=_blank style='color:#2F92EE;'>#NET#</a>, beContent=null, objectType=article, 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status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1390414, encodeId=959b139041435, content=<a href='/topic/show?id=22c6101695c9' target=_blank style='color:#2F92EE;'>#骨折风险#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=50, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=101695, encryptionId=22c6101695c9, topicName=骨折风险)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=21015, createdName=heli0118, createdTime=Sun Nov 10 13:01:00 CST 2019, time=2019-11-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1408500, encodeId=9d1c140850033, content=<a href='/topic/show?id=92021020e814' target=_blank style='color:#2F92EE;'>#髋部#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=61, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=102078, encryptionId=92021020e814, topicName=髋部)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=293f2750231, createdName=liuquan, createdTime=Sun Nov 10 13:01:00 CST 2019, time=2019-11-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1526651, encodeId=2649152665156, content=<a href='/topic/show?id=2fe6e88863a' target=_blank style='color:#2F92EE;'>#绝经后女性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=78886, encryptionId=2fe6e88863a, topicName=绝经后女性)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=b55511745984, createdName=chenhongpeng, createdTime=Sun Nov 10 13:01:00 CST 2019, time=2019-11-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1631622, encodeId=3425163162219, content=<a href='/topic/show?id=6395e888343' target=_blank style='color:#2F92EE;'>#绝经后#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=78883, encryptionId=6395e888343, topicName=绝经后)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=395f25, createdName=爆笑小医, createdTime=Sun Nov 10 13:01:00 CST 2019, time=2019-11-10, status=1, ipAttribution=)]
  7. [GetPortalCommentsPageByObjectIdResponse(id=1234134, encodeId=71c6123413411, content=<a href='/topic/show?id=baaa1020837e' target=_blank style='color:#2F92EE;'>#髋部骨折#</a>是<a href='/topic/show?id=fd3a1018623d' target=_blank style='color:#2F92EE;'>#骨质疏松#</a>的重要并发症, beContent=null, objectType=article, channel=null, level=null, likeNumber=164, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=102083, encryptionId=baaa1020837e, topicName=髋部骨折), TopicDto(id=101862, encryptionId=fd3a1018623d, topicName=骨质疏松)], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/Random/55971dc507c93968175ce7cc1e177b372a83869f.jpg, createdBy=f63e4754896, createdName=小小医者, createdTime=Sat Jul 23 03:20:00 CST 2022, time=2022-07-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1734184, encodeId=5c191e341848b, content=<a href='/topic/show?id=d4f412668a4' target=_blank style='color:#2F92EE;'>#NET#</a>, beContent=null, objectType=article, 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status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1390414, encodeId=959b139041435, content=<a href='/topic/show?id=22c6101695c9' target=_blank style='color:#2F92EE;'>#骨折风险#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=50, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=101695, encryptionId=22c6101695c9, topicName=骨折风险)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=21015, createdName=heli0118, createdTime=Sun Nov 10 13:01:00 CST 2019, time=2019-11-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1408500, encodeId=9d1c140850033, content=<a href='/topic/show?id=92021020e814' target=_blank style='color:#2F92EE;'>#髋部#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=61, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=102078, encryptionId=92021020e814, topicName=髋部)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=293f2750231, createdName=liuquan, createdTime=Sun Nov 10 13:01:00 CST 2019, time=2019-11-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1526651, encodeId=2649152665156, content=<a href='/topic/show?id=2fe6e88863a' target=_blank style='color:#2F92EE;'>#绝经后女性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=78886, encryptionId=2fe6e88863a, topicName=绝经后女性)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=b55511745984, createdName=chenhongpeng, createdTime=Sun Nov 10 13:01:00 CST 2019, time=2019-11-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1631622, encodeId=3425163162219, content=<a href='/topic/show?id=6395e888343' target=_blank style='color:#2F92EE;'>#绝经后#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=78883, encryptionId=6395e888343, topicName=绝经后)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=395f25, createdName=爆笑小医, createdTime=Sun Nov 10 13:01:00 CST 2019, time=2019-11-10, status=1, ipAttribution=)]
    2019-11-10 liuquan
  8. 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