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啤酒中的苦味成分能抑制老年痴呆症

2016-12-04 佚名 生物探索

日本麒麟啤酒株式会社和东京大学、学习院大学的共同研究小组日在12月1日到3日召开的日本认知症学会学术集会上发表了一项新发现:啤酒中啤酒花苦味成分的异α酸有抑制阿尔茨海默病的效果。据日本厚生劳动省介绍,日本国内共有462万(2012年)老年痴呆症患者,据推测其中阿尔茨海默病人数约占7成。随着年龄的增加,脑内积聚的“β淀粉样蛋白”是导致老年痴呆症的主要原因。到现在为止的流行病学等的研究,适量酒类的摄取

日本麒麟啤酒株式会社和东京大学、学习院大学的共同研究小组日在12月1日到3日召开的日本认知症学会学术集会上发表了一项新发现:啤酒中啤酒花苦味成分的异α酸有抑制阿尔茨海默病的效果。

据日本厚生劳动省介绍,日本国内共有462万(2012年)老年痴呆症患者,据推测其中阿尔茨海默病人数约占7成。随着年龄的增加,脑内积聚的“β淀粉样蛋白”是导致老年痴呆症的主要原因。

到现在为止的流行病学等的研究,适量酒类的摄取可以预防老年痴呆被报告过。特别红葡萄酒的多酚对老年痴呆症的效果有很多研究报告,不过,关于啤酒的成分没有充分的研究。

异α-酸有除去β淀粉样蛋白的作用

麒麟啤酒株式会社和东京大学的中山裕之教授等人在实验中发现,啤酒泡沫本身的苦味成分“异α-酸”能激活脑内的免疫细胞——“小神经胶质细胞”,有除去β淀粉样蛋白的作用。

通过在3个月内对阿尔茨海默病模型鼠饲喂含有异α酸的饲料后对小鼠进行行为药理学试验:对β淀粉样蛋白的量、炎症物质的检测,以及对神经细胞突触量的测量,同时对脑内废旧物质去除的微观细胞的活性状态进行评价。另外也对小鼠进行新奇物体认识这样的记忆评价的行动试验。



服食过异α-酸饵料的小鼠和普通的小鼠相比,β淀粉样蛋白约减少5成,脑内的炎症被缓和,脑内废物消除活动性和抗炎症活性提高,神经细胞的突触量也增加。行动药理的结果显示认识功能得到改善。

根据以上结果异α-酸能够激活小神经胶质细胞去除脑内废旧物质,显示了对阿尔兹海默症发展的抑制作用。

原始出处

ホップ由来のビール苦味成分であるイソα酸のアルツハイマー病予防に関する作用機序を解明

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  1. [GetPortalCommentsPageByObjectIdResponse(id=172108, encodeId=c2b01e2108ff, content=哈哈以后就靠喝啤酒预防痴呆啦, beContent=null, objectType=article, channel=null, level=null, likeNumber=61, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=071c2012037, createdName=wmu姿, createdTime=Mon Jan 23 09:51:49 CST 2017, time=2017-01-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1836135, encodeId=b4a4183613529, content=<a href='/topic/show?id=4613e1212fc' target=_blank style='color:#2F92EE;'>#痴呆症#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=49, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=71212, encryptionId=4613e1212fc, topicName=痴呆症)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4c37265, createdName=zhaojie88, createdTime=Sat May 20 09:00:00 CST 2017, time=2017-05-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=162890, encodeId=852c1628902a, content=这个量挺难把握的!, beContent=null, objectType=article, channel=null, level=null, likeNumber=65, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20161215/IMG585172F1601148210.jpg, createdBy=cac71958317, createdName=琥珀西岸, createdTime=Thu Dec 15 00:22:46 CST 2016, time=2016-12-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=162229, encodeId=0ee81622297d, content=看来啤酒?的好处还是真不少啊!, beContent=null, objectType=article, channel=null, level=null, likeNumber=79, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7s7ZCKOmmbBTD6nE7gcd5OZpvyGEzkxBP3S275k5ZJVrsPkotZhBglRHM9rKvcj1OgkssqhcnoPw8zIaMZTF8c/0, createdBy=4c441942088, createdName=ylzr123, createdTime=Mon Dec 12 19:53:17 CST 2016, time=2016-12-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=160546, encodeId=fa9316054665, content=我要去学喝酒, beContent=null, objectType=article, channel=null, level=null, likeNumber=80, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5Rzegz2kicwSDGST4gkzMm8229KtEaV7JEushLtsOJ4OweeyQ7oiaqU73G1eVialdQSZrH7DWxTgR8pYZ/0, createdBy=e81f1959878, createdName=小大夫快跑, createdTime=Tue Dec 06 05:43:44 CST 2016, time=2016-12-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=160435, encodeId=458516043582, content=有报道说,饮酒可加快动脉粥样硬化,现有报道说,适量饮酒对身体有益。这个程度,很难把握~, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160313/IMG56E50DEC424F44672.jpg, createdBy=ce5b1699635, createdName=Lisa971, createdTime=Mon Dec 05 13:54:24 CST 2016, time=2016-12-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=160273, encodeId=233d1602e3cf, content=啤酒?喝起来, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=445f1740270, createdName=meiliwuxian, createdTime=Sun Dec 04 22:30:35 CST 2016, time=2016-12-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=160263, encodeId=3c1916026348, content=有时候正确的运用酒和烟是有利于我们身体健康的!, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=76491981781, createdName=1e184d7bm65(暂无匿称), createdTime=Sun Dec 04 21:45:01 CST 2016, time=2016-12-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=160250, encodeId=a20c16025024, content=但啤酒中也有一定的有害成分,所以到底是益处多还是害处多?这值得思考, beContent=null, objectType=article, channel=null, level=null, likeNumber=25, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://q.qlogo.cn/qqapp/1103841572/651DB1E2868EC9DCC2604FF273E68010/100, createdBy=b4d61981770, createdName=KevinSong, createdTime=Sun Dec 04 21:21:16 CST 2016, time=2016-12-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=160209, encodeId=6a69160209eb, content=多喝啤酒, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://q.qlogo.cn/qqapp/101296147/6D9C89AB36A71EA450A5729452654834/100, createdBy=b07f1943308, createdName=博雷, createdTime=Sun Dec 04 14:41:51 CST 2016, time=2016-12-04, status=1, ipAttribution=)]
    2017-01-23 wmu姿

    哈哈以后就靠喝啤酒预防痴呆啦

    0

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  3. [GetPortalCommentsPageByObjectIdResponse(id=172108, encodeId=c2b01e2108ff, content=哈哈以后就靠喝啤酒预防痴呆啦, beContent=null, objectType=article, channel=null, level=null, likeNumber=61, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=071c2012037, createdName=wmu姿, createdTime=Mon Jan 23 09:51:49 CST 2017, time=2017-01-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1836135, encodeId=b4a4183613529, content=<a href='/topic/show?id=4613e1212fc' target=_blank style='color:#2F92EE;'>#痴呆症#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=49, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=71212, encryptionId=4613e1212fc, topicName=痴呆症)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4c37265, createdName=zhaojie88, createdTime=Sat May 20 09:00:00 CST 2017, time=2017-05-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=162890, encodeId=852c1628902a, content=这个量挺难把握的!, beContent=null, objectType=article, channel=null, level=null, likeNumber=65, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20161215/IMG585172F1601148210.jpg, createdBy=cac71958317, createdName=琥珀西岸, createdTime=Thu Dec 15 00:22:46 CST 2016, time=2016-12-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=162229, encodeId=0ee81622297d, content=看来啤酒?的好处还是真不少啊!, beContent=null, objectType=article, channel=null, level=null, likeNumber=79, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7s7ZCKOmmbBTD6nE7gcd5OZpvyGEzkxBP3S275k5ZJVrsPkotZhBglRHM9rKvcj1OgkssqhcnoPw8zIaMZTF8c/0, createdBy=4c441942088, createdName=ylzr123, createdTime=Mon Dec 12 19:53:17 CST 2016, time=2016-12-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=160546, encodeId=fa9316054665, content=我要去学喝酒, beContent=null, objectType=article, channel=null, level=null, likeNumber=80, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5Rzegz2kicwSDGST4gkzMm8229KtEaV7JEushLtsOJ4OweeyQ7oiaqU73G1eVialdQSZrH7DWxTgR8pYZ/0, createdBy=e81f1959878, createdName=小大夫快跑, createdTime=Tue Dec 06 05:43:44 CST 2016, time=2016-12-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=160435, encodeId=458516043582, content=有报道说,饮酒可加快动脉粥样硬化,现有报道说,适量饮酒对身体有益。这个程度,很难把握~, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160313/IMG56E50DEC424F44672.jpg, createdBy=ce5b1699635, createdName=Lisa971, createdTime=Mon Dec 05 13:54:24 CST 2016, time=2016-12-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=160273, encodeId=233d1602e3cf, content=啤酒?喝起来, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=445f1740270, createdName=meiliwuxian, createdTime=Sun Dec 04 22:30:35 CST 2016, time=2016-12-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=160263, encodeId=3c1916026348, content=有时候正确的运用酒和烟是有利于我们身体健康的!, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=76491981781, createdName=1e184d7bm65(暂无匿称), createdTime=Sun Dec 04 21:45:01 CST 2016, time=2016-12-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=160250, encodeId=a20c16025024, content=但啤酒中也有一定的有害成分,所以到底是益处多还是害处多?这值得思考, beContent=null, objectType=article, channel=null, level=null, likeNumber=25, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://q.qlogo.cn/qqapp/1103841572/651DB1E2868EC9DCC2604FF273E68010/100, createdBy=b4d61981770, createdName=KevinSong, createdTime=Sun Dec 04 21:21:16 CST 2016, time=2016-12-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=160209, encodeId=6a69160209eb, content=多喝啤酒, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://q.qlogo.cn/qqapp/101296147/6D9C89AB36A71EA450A5729452654834/100, createdBy=b07f1943308, createdName=博雷, createdTime=Sun Dec 04 14:41:51 CST 2016, time=2016-12-04, status=1, ipAttribution=)]
    2016-12-15 琥珀西岸

    这个量挺难把握的!

    0

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    2016-12-12 ylzr123

    看来啤酒?的好处还是真不少啊!

    0

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    2016-12-06 小大夫快跑

    我要去学喝酒

    0

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    2016-12-05 Lisa971

    有报道说,饮酒可加快动脉粥样硬化,现有报道说,适量饮酒对身体有益。这个程度,很难把握~

    0

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    2016-12-04 meiliwuxian

    啤酒?喝起来

    0

  8. [GetPortalCommentsPageByObjectIdResponse(id=172108, encodeId=c2b01e2108ff, content=哈哈以后就靠喝啤酒预防痴呆啦, beContent=null, objectType=article, channel=null, level=null, likeNumber=61, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=071c2012037, createdName=wmu姿, createdTime=Mon Jan 23 09:51:49 CST 2017, time=2017-01-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1836135, encodeId=b4a4183613529, content=<a href='/topic/show?id=4613e1212fc' target=_blank style='color:#2F92EE;'>#痴呆症#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=49, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=71212, encryptionId=4613e1212fc, topicName=痴呆症)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4c37265, createdName=zhaojie88, createdTime=Sat May 20 09:00:00 CST 2017, time=2017-05-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=162890, encodeId=852c1628902a, content=这个量挺难把握的!, beContent=null, objectType=article, channel=null, level=null, likeNumber=65, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20161215/IMG585172F1601148210.jpg, createdBy=cac71958317, createdName=琥珀西岸, createdTime=Thu Dec 15 00:22:46 CST 2016, time=2016-12-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=162229, encodeId=0ee81622297d, content=看来啤酒?的好处还是真不少啊!, beContent=null, objectType=article, channel=null, level=null, likeNumber=79, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7s7ZCKOmmbBTD6nE7gcd5OZpvyGEzkxBP3S275k5ZJVrsPkotZhBglRHM9rKvcj1OgkssqhcnoPw8zIaMZTF8c/0, createdBy=4c441942088, createdName=ylzr123, createdTime=Mon Dec 12 19:53:17 CST 2016, time=2016-12-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=160546, encodeId=fa9316054665, content=我要去学喝酒, beContent=null, objectType=article, channel=null, level=null, likeNumber=80, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5Rzegz2kicwSDGST4gkzMm8229KtEaV7JEushLtsOJ4OweeyQ7oiaqU73G1eVialdQSZrH7DWxTgR8pYZ/0, createdBy=e81f1959878, createdName=小大夫快跑, createdTime=Tue Dec 06 05:43:44 CST 2016, time=2016-12-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=160435, encodeId=458516043582, content=有报道说,饮酒可加快动脉粥样硬化,现有报道说,适量饮酒对身体有益。这个程度,很难把握~, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160313/IMG56E50DEC424F44672.jpg, createdBy=ce5b1699635, createdName=Lisa971, createdTime=Mon Dec 05 13:54:24 CST 2016, time=2016-12-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=160273, encodeId=233d1602e3cf, content=啤酒?喝起来, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=445f1740270, createdName=meiliwuxian, createdTime=Sun Dec 04 22:30:35 CST 2016, time=2016-12-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=160263, encodeId=3c1916026348, content=有时候正确的运用酒和烟是有利于我们身体健康的!, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=76491981781, createdName=1e184d7bm65(暂无匿称), createdTime=Sun Dec 04 21:45:01 CST 2016, time=2016-12-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=160250, encodeId=a20c16025024, content=但啤酒中也有一定的有害成分,所以到底是益处多还是害处多?这值得思考, beContent=null, objectType=article, channel=null, level=null, likeNumber=25, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://q.qlogo.cn/qqapp/1103841572/651DB1E2868EC9DCC2604FF273E68010/100, createdBy=b4d61981770, createdName=KevinSong, createdTime=Sun Dec 04 21:21:16 CST 2016, time=2016-12-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=160209, encodeId=6a69160209eb, content=多喝啤酒, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://q.qlogo.cn/qqapp/101296147/6D9C89AB36A71EA450A5729452654834/100, createdBy=b07f1943308, createdName=博雷, createdTime=Sun Dec 04 14:41:51 CST 2016, time=2016-12-04, status=1, ipAttribution=)]
    2016-12-04 1e184d7bm65(暂无匿称)

    有时候正确的运用酒和烟是有利于我们身体健康的!

    0

  9. [GetPortalCommentsPageByObjectIdResponse(id=172108, encodeId=c2b01e2108ff, content=哈哈以后就靠喝啤酒预防痴呆啦, beContent=null, objectType=article, channel=null, level=null, likeNumber=61, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=071c2012037, createdName=wmu姿, createdTime=Mon Jan 23 09:51:49 CST 2017, time=2017-01-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1836135, encodeId=b4a4183613529, content=<a href='/topic/show?id=4613e1212fc' target=_blank style='color:#2F92EE;'>#痴呆症#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=49, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=71212, encryptionId=4613e1212fc, topicName=痴呆症)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4c37265, createdName=zhaojie88, createdTime=Sat May 20 09:00:00 CST 2017, time=2017-05-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=162890, encodeId=852c1628902a, content=这个量挺难把握的!, beContent=null, objectType=article, channel=null, level=null, likeNumber=65, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20161215/IMG585172F1601148210.jpg, createdBy=cac71958317, createdName=琥珀西岸, createdTime=Thu Dec 15 00:22:46 CST 2016, time=2016-12-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=162229, encodeId=0ee81622297d, content=看来啤酒?的好处还是真不少啊!, beContent=null, objectType=article, channel=null, level=null, likeNumber=79, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7s7ZCKOmmbBTD6nE7gcd5OZpvyGEzkxBP3S275k5ZJVrsPkotZhBglRHM9rKvcj1OgkssqhcnoPw8zIaMZTF8c/0, createdBy=4c441942088, createdName=ylzr123, createdTime=Mon Dec 12 19:53:17 CST 2016, time=2016-12-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=160546, encodeId=fa9316054665, content=我要去学喝酒, beContent=null, objectType=article, channel=null, level=null, likeNumber=80, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5Rzegz2kicwSDGST4gkzMm8229KtEaV7JEushLtsOJ4OweeyQ7oiaqU73G1eVialdQSZrH7DWxTgR8pYZ/0, createdBy=e81f1959878, createdName=小大夫快跑, createdTime=Tue Dec 06 05:43:44 CST 2016, time=2016-12-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=160435, encodeId=458516043582, content=有报道说,饮酒可加快动脉粥样硬化,现有报道说,适量饮酒对身体有益。这个程度,很难把握~, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160313/IMG56E50DEC424F44672.jpg, createdBy=ce5b1699635, createdName=Lisa971, createdTime=Mon Dec 05 13:54:24 CST 2016, time=2016-12-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=160273, encodeId=233d1602e3cf, content=啤酒?喝起来, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=445f1740270, createdName=meiliwuxian, createdTime=Sun Dec 04 22:30:35 CST 2016, time=2016-12-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=160263, encodeId=3c1916026348, content=有时候正确的运用酒和烟是有利于我们身体健康的!, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=76491981781, createdName=1e184d7bm65(暂无匿称), createdTime=Sun Dec 04 21:45:01 CST 2016, time=2016-12-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=160250, encodeId=a20c16025024, content=但啤酒中也有一定的有害成分,所以到底是益处多还是害处多?这值得思考, beContent=null, objectType=article, channel=null, level=null, likeNumber=25, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://q.qlogo.cn/qqapp/1103841572/651DB1E2868EC9DCC2604FF273E68010/100, createdBy=b4d61981770, createdName=KevinSong, createdTime=Sun Dec 04 21:21:16 CST 2016, time=2016-12-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=160209, encodeId=6a69160209eb, content=多喝啤酒, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://q.qlogo.cn/qqapp/101296147/6D9C89AB36A71EA450A5729452654834/100, createdBy=b07f1943308, createdName=博雷, createdTime=Sun Dec 04 14:41:51 CST 2016, time=2016-12-04, status=1, ipAttribution=)]
    2016-12-04 KevinSong

    但啤酒中也有一定的有害成分,所以到底是益处多还是害处多?这值得思考

    0

  10. [GetPortalCommentsPageByObjectIdResponse(id=172108, encodeId=c2b01e2108ff, content=哈哈以后就靠喝啤酒预防痴呆啦, beContent=null, objectType=article, channel=null, level=null, likeNumber=61, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=071c2012037, createdName=wmu姿, createdTime=Mon Jan 23 09:51:49 CST 2017, time=2017-01-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1836135, encodeId=b4a4183613529, content=<a href='/topic/show?id=4613e1212fc' target=_blank style='color:#2F92EE;'>#痴呆症#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=49, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=71212, encryptionId=4613e1212fc, topicName=痴呆症)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4c37265, createdName=zhaojie88, createdTime=Sat May 20 09:00:00 CST 2017, time=2017-05-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=162890, encodeId=852c1628902a, content=这个量挺难把握的!, beContent=null, objectType=article, channel=null, level=null, likeNumber=65, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20161215/IMG585172F1601148210.jpg, createdBy=cac71958317, createdName=琥珀西岸, createdTime=Thu Dec 15 00:22:46 CST 2016, time=2016-12-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=162229, encodeId=0ee81622297d, content=看来啤酒?的好处还是真不少啊!, beContent=null, objectType=article, channel=null, level=null, likeNumber=79, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7s7ZCKOmmbBTD6nE7gcd5OZpvyGEzkxBP3S275k5ZJVrsPkotZhBglRHM9rKvcj1OgkssqhcnoPw8zIaMZTF8c/0, createdBy=4c441942088, createdName=ylzr123, createdTime=Mon Dec 12 19:53:17 CST 2016, time=2016-12-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=160546, encodeId=fa9316054665, content=我要去学喝酒, beContent=null, objectType=article, channel=null, level=null, likeNumber=80, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5Rzegz2kicwSDGST4gkzMm8229KtEaV7JEushLtsOJ4OweeyQ7oiaqU73G1eVialdQSZrH7DWxTgR8pYZ/0, createdBy=e81f1959878, createdName=小大夫快跑, createdTime=Tue Dec 06 05:43:44 CST 2016, time=2016-12-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=160435, encodeId=458516043582, content=有报道说,饮酒可加快动脉粥样硬化,现有报道说,适量饮酒对身体有益。这个程度,很难把握~, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160313/IMG56E50DEC424F44672.jpg, createdBy=ce5b1699635, createdName=Lisa971, createdTime=Mon Dec 05 13:54:24 CST 2016, time=2016-12-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=160273, encodeId=233d1602e3cf, content=啤酒?喝起来, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=445f1740270, createdName=meiliwuxian, createdTime=Sun Dec 04 22:30:35 CST 2016, time=2016-12-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=160263, encodeId=3c1916026348, content=有时候正确的运用酒和烟是有利于我们身体健康的!, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=76491981781, createdName=1e184d7bm65(暂无匿称), createdTime=Sun Dec 04 21:45:01 CST 2016, time=2016-12-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=160250, encodeId=a20c16025024, content=但啤酒中也有一定的有害成分,所以到底是益处多还是害处多?这值得思考, beContent=null, objectType=article, channel=null, level=null, likeNumber=25, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://q.qlogo.cn/qqapp/1103841572/651DB1E2868EC9DCC2604FF273E68010/100, createdBy=b4d61981770, createdName=KevinSong, createdTime=Sun Dec 04 21:21:16 CST 2016, time=2016-12-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=160209, encodeId=6a69160209eb, content=多喝啤酒, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://q.qlogo.cn/qqapp/101296147/6D9C89AB36A71EA450A5729452654834/100, createdBy=b07f1943308, createdName=博雷, createdTime=Sun Dec 04 14:41:51 CST 2016, time=2016-12-04, status=1, ipAttribution=)]
    2016-12-04 博雷

    多喝啤酒

    0

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