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Menopause: BMI不足以定义绝经后妇女肥胖情况

2017-11-20 海北 MedSci原创

体重指数(BMI)是临床和人群健康研究中广泛使用的肥胖状态指标。然而,人们对于将BMI作为衡量绝经后妇女肥胖程度的指标存在质疑。

体重指数(BMI)是临床和人群健康研究中广泛使用的肥胖状态指标。然而,人们对于将BMI作为衡量绝经后妇女肥胖程度的指标存在质疑。BMI是肥胖的间接指标,不能区分瘦肉和脂肪。与BMI不同,Dualenergy X射线吸收仪(DXA)可以直接测量人体的脂肪含量,被认为是肥胖测量的金标准。

来自纽约州立大学布法罗分校的研究人员进行了一项研究,该研究的目的是检查相对于通过DXA扫描测量的总体脂肪百分比,使用体重指数BMI来识别绝经后妇女的肥胖程度的有效性。

参加布法罗OsteoPerio研究的1329名绝经后妇女的数据被用于该项分析。在基线时,女性的年龄从53岁到85岁不等。肥胖定义为BMI 30 kg/m2,体脂百分比(BF%)大于35%,38%或40%。研究人员计算了敏感性,特异性,阳性预测值和阴性预测值,来评估BMI定义的肥胖相对BF%的有效性。研究人员使用图形工具(例如散点图和受试者工作特征曲线)进一步探索了BMI相对于BF%的有效性。约登J指数被用来确定每个BF%定义的肥胖水平的经验最优BMI切点。

结果显示,35%体脂肪对BMI肥胖的敏感性为32.4%,38%体脂肪为44.6%,40%体脂肪为55.2%。相应的特异性值分别为99.3%,97.1%和94.6%。按照约登指数,定义肥胖的经验最佳BMI切点是: 35%BF为24.9 kg / m2,38%BF为26.49 kg / m2,40%BF为27.05 kg / m2

结果表明,30kg/m2BMI切点似乎不是绝经后妇女真正肥胖状况的适当指标。


原始出处:

Hailey R. Banack et al. Is BMI a valid measure of obesity in postmenopausal women? Menopause, 2017; 1 DOI: 10.1097/GME.0000000000000989


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    2017-11-22 zxxiang
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    2017-11-20 Chongyang Zhang

    签到学习了很多人

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