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Science:意志力确实能促进脊髓损伤的康复

2015-10-13 MedSci MedSci原创

人们总是说,在面对病魔的时候要积极配合治疗,心态好的人病也好得快。但这种言论一直缺乏科学证据,在许多人眼里不过是老生常谈。最近日本科学家们终于证明,精神动力的确可以帮助患者战胜疾病。脊髓损伤和中风都是毁灭性的疾病,会令患者突然丧失独立生活的能力(语言、手和运动能力受损)。帮助这些患者恢复身体机能,一直是医学和科研领域的重要课题。从临床表现上看,精神动力(motivation)似乎有助于这些患者恢复

人们总是说,在面对病魔的时候要积极配合治疗,心态好的人病也好得快。但这种言论一直缺乏科学证据,在许多人眼里不过是老生常谈。最近日本科学家们终于证明,精神动力的确可以帮助患者战胜疾病。

脊髓损伤和中风都是毁灭性的疾病,会令患者突然丧失独立生活的能力(语言、手和运动能力受损)。帮助这些患者恢复身体机能,一直是医学和科研领域的重要课题。从临床表现上看,精神动力(motivation)似乎有助于这些患者恢复运动机能,而抑郁症状会延缓患者的机能恢复。那么,精神动力究竟对患者产生了怎样的影响呢?

日本NIPS(National Institute for Physiological Sciences)的副教授Yukio Nishimura领导研究团队对此进行了深入研究。他们发现,大脑中控制精神动力的伏隔核(nucleus accumbens),能够激活大脑运动皮层的活性,在脊髓损伤的康复初期促进运动机能的恢复。这一研究成果发表在十月二日的Science杂志上。

伏隔核是大脑中与奖赏、情感、激励和成瘾有关的重要区域,而运动皮层是支配人体运动的高级中枢。研究人员建立了受到脊髓损伤的猴子模型,由此分析了伏隔核神经活性与运动皮层神经活性之间的关系。他们在猴子脊髓受伤一个月后,暂时性阻断了其伏隔核活性。研究显示,这些猴子运动皮层的活性受到抑制,手指灵活性的恢复受到显著影响。而对照组的猴子在康复阶段没有出现这种手部运动缺陷。

这项研究表明,在猴子的早期康复阶段,伏隔核能够对手部控制功能起作用,刺激伏隔核活性可以促进这种运动机能的恢复。“我们的工作说明,在大脑损伤(包括脊髓损伤)的早期阶段,激励患者对于其运动机能的恢复非常重要。为这些患者提供心理支持是很有意义的,”


原始出处:

Sawada M, Kato K, Kunieda T, Mikuni N, Miyamoto S, Onoe H, Isa T, Nishimura Y.Function of the nucleus accumbens in motor control during recovery after spinal cord injury. Science. 2015 Oct 2;350(6256):98-101. 

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    2015-12-08 liushui8012

    日本不一定可信!

    0

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    2015-11-24 老段

    有科学价值吗?

    0

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    2015-11-17 limin0214

    日本的科研可信度不一定哟

    0

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    2015-11-04 Asteroid

    这都行

    0

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    2015-10-31 liusanxin

    这都行,要锻炼意志力了

    0

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    2015-10-24 杨子

    意志力改变世界

    0

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    2015-10-18 sunlong28

    谢谢分享~

    0

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    2015-10-18 sunlong28

    为了积分我也是拼了~

    0

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    2015-10-18 sunlong28

    赞一个~

    0

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    2015-10-15 jichang

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