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Stroke:脑淀粉样血管病的急性卒中患者血管内治疗效果分析

2021-08-21 MedSci原创 MedSci原创

血管内血栓切除术联合或不联合溶栓对伴有CAA的急性缺血性卒中患者都有益,但与较差的功能结局相关。

近日,血管疾病领域权威杂志Stroke上发表了一篇研究文章,研究人员旨在比较血管内血栓切除术在伴有和不伴有脑淀粉样血管病(CAA)的急性缺血性卒中患者中的结局。


研究人员纳入了伴有或不伴有可能CAA的急性缺血性卒中和血管内血栓切除术患者,并分析了受试者的基线特征、手术参数和90天后功能结局。

162名急性缺血性卒中患者中有28名(17.3%)在血管内血栓切除术前伴有根据铁敏感磁共振成像诊断的CAA。CAA患者不太可能获得良好的90天结局(14.3% vs. 37.8%)。

美国国立卫生研究院卒中量表评分(调整后的比值比为0.88;P<0.001)、成功再通(调整后的比值比6.82;P=0.005)和CAA(调整后的比值比0.28;P=0.049)是独立的结局预测因素。静脉溶栓与CAA的良好结局增加相关(36.3% vs. 0%,P=0.031)。
 
由此可见,血管内血栓切除术联合或不联合溶栓对伴有CAA的急性缺血性卒中患者都有益,但与较差的功能结局相关。

原始出处:

Johannes M. Weller.et al.Endovascular Treatment for Acute Stroke in Cerebral Amyloid Angiopathy.stroke.2021.https://www.ahajournals.org/doi/10.1161/STROKEAHA.120.033014

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topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=内科新手, createdTime=Sat Aug 21 18:50:32 CST 2021, time=2021-08-21, status=1, ipAttribution=)]
    2021-09-22 452946589

    学习了

    0

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  8. 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topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=内科新手, createdTime=Sat Aug 21 18:50:32 CST 2021, time=2021-08-21, status=1, ipAttribution=)]
  9. [GetPortalCommentsPageByObjectIdResponse(id=2046682, encodeId=6d26204668211, content=<a href='/topic/show?id=9b708491280' target=_blank style='color:#2F92EE;'>#脑淀粉样#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=66, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=84912, encryptionId=9b708491280, topicName=脑淀粉样)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=dab8203, createdName=zsyan, createdTime=Sun Feb 27 03:50:32 CST 2022, time=2022-02-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1720406, encodeId=c9891e204067f, content=<a href='/topic/show?id=915c3604e6b' target=_blank style='color:#2F92EE;'>#卒中患者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=62, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=36047, encryptionId=915c3604e6b, topicName=卒中患者)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=940232842333, 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topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=df324723890, createdName=452946589, createdTime=Wed Sep 22 03:27:41 CST 2021, time=2021-09-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1284472, encodeId=d8b412844e23e, content=<a href='/topic/show?id=d2155222281' target=_blank style='color:#2F92EE;'>#急性卒中#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=52222, encryptionId=d2155222281, topicName=急性卒中)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=afa4194, createdName=cenghis, createdTime=Mon Aug 23 06:50:32 CST 2021, time=2021-08-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1628784, encodeId=fbcb1628e8430, content=<a href='/topic/show?id=1c748491616' target=_blank style='color:#2F92EE;'>#脑淀粉样血管病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=84916, encryptionId=1c748491616, topicName=脑淀粉样血管病)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ac7921195890, createdName=Smile2687, createdTime=Mon Aug 23 06:50:32 CST 2021, time=2021-08-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1026938, encodeId=9cfb1026938e6, content=卒中虽然是临床上常见病,溶栓,取栓等血管内治疗也很成熟,但是仍然有很多未知问题有待认知!, beContent=null, objectType=article, channel=null, level=null, likeNumber=117, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=健健, createdTime=Sat Aug 21 18:50:32 CST 2021, time=2021-08-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1033095, encodeId=c67c10330959a, content=谢谢梅斯提供这么好的信息,学到很多, beContent=null, objectType=article, channel=null, level=null, likeNumber=78, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=内科新手, createdTime=Sat Aug 21 18:50:32 CST 2021, time=2021-08-21, status=1, ipAttribution=)]
    2021-08-21 健健

    卒中虽然是临床上常见病,溶栓,取栓等血管内治疗也很成熟,但是仍然有很多未知问题有待认知!

    0

  10. 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topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=df324723890, createdName=452946589, createdTime=Wed Sep 22 03:27:41 CST 2021, time=2021-09-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1284472, encodeId=d8b412844e23e, content=<a href='/topic/show?id=d2155222281' target=_blank style='color:#2F92EE;'>#急性卒中#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=52222, encryptionId=d2155222281, topicName=急性卒中)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=afa4194, createdName=cenghis, createdTime=Mon Aug 23 06:50:32 CST 2021, time=2021-08-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1628784, encodeId=fbcb1628e8430, content=<a href='/topic/show?id=1c748491616' target=_blank style='color:#2F92EE;'>#脑淀粉样血管病#</a>, beContent=null, objectType=article, channel=null, level=null, 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topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=内科新手, createdTime=Sat Aug 21 18:50:32 CST 2021, time=2021-08-21, status=1, ipAttribution=)]
    2021-08-21 内科新手

    谢谢梅斯提供这么好的信息,学到很多

    0

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